914088-64-5

914088-64-5 structure

Name: Cazpaullone
Chemical Name: Pyrido[3',2':2,3]azepino[4,5-b]indole-9-carbonitrile, 5,6,7,12-tetrahydro-6-oxo
CAS Number: 914088-64-5
Molecular Formula: C₁₆H₁₀N₄O
Molecular Weight: 274.27700
Catalog: Signaling Pathways PI3K/Akt/mTOR GSK-3
Create Date: 2017-05-23 09:28:58
Modify Date: 2025-08-27 11:15:10
Cazpaullone is a glycogen synthase kinase-3 (GSK-3) inhibitor. Cazpaullone can activate pancreatic beta cell protection and replication. Cazpaullone can be used for the research of diabetes[1].

Name	Pyrido[3',2':2,3]azepino[4,5-b]indole-9-carbonitrile, 5,6,7,12-tetrahydro-6-oxo
Synonyms	CAZPAULLONE Cazpaullone

Description	Cazpaullone is a glycogen synthase kinase-3 (GSK-3) inhibitor. Cazpaullone can activate pancreatic beta cell protection and replication. Cazpaullone can be used for the research of diabetes[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Metabolic Disease Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3
References	[1]. Stukenbrock H, et al. 9-cyano-1-azapaullone (cazpaullone), a glycogen synthase kinase-3 (GSK-3) inhibitor activating pancreatic beta cell protection and replication. J Med Chem. 2008 Apr 10;51(7):2196-207.