100361-18-0
100361-18-0 structure
- Name: 1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
- Chemical Name: 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylic Acid
- CAS Number: 100361-18-0
- Molecular Formula: C12H8ClFN2O3
- Molecular Weight: 282.655
- Catalog: Chemical reagent Organic reagent Aromatic hydrocarbon
- Create Date: 2018-05-23 08:00:00
- Modify Date: 2026-07-07 09:49:08
| Name | 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylic Acid |
|---|---|
| Synonyms |
Nalidixic acid cyclopropyl
7-Chloro-1-cyclopropyl-1,4-dihydro-3-oxo-1,8-naphthyridine-3-cboxylic aci 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYIDINE CBOXYLIC ACID 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1 1-Cyclopropyl-6-fluoro-7-chloride-4-oxo-1 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-CboxylicAci 7-Chloro-1-cyclopropyl-6-fluor T66 BV EN GNJ CVQ HG IF E- AL3TJ 1-CYCLOPROPYL-6-FLUORO-7-CHLORIDE-4-OXO-1,4-DIHYDRO-1,8-NAPTHYRIDINE-3-CBOXYLIE ACID 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 3-Cboxy-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-cboxylic acid 7-Chloro-1-cycloprop 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic Acid 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Qxoquinoline-3-CboxylicAcid 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyl ridine cbox.acid 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthylridine carboxylic acid 1,8-Naphthyridine-3-cboxylicacid, 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo 8-naphthyridine-3-cboxylic acid 1-Cyclopropyl-6-Fluoro-7-Chloro-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Cboxylie acid 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYLPYRIDINECBOXYLIC ACID 1-CYCLOPROPYL-6-FLUORO-7-CHLORIDE-4-OXO-1,4-DIHYDRO-1,8-NAPTHYRIDINE-3-CBOXYLIC ACID 1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-cboxylic acid 1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-napthyridine-3-cboxylic acid 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Cboxylic 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-cboxylic acid 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-Ox (S)-2-amino-3-(2,4-diMethylphenyl)propanoic acid 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-1,8-Naphthyridin-3-Cboxylic Acid Gemifloxacin 7-Chloro Impurity 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-cboxylicacid |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 485.9±45.0 °C at 760 mmHg |
| Melting Point | 224 °C |
| Molecular Formula | C12H8ClFN2O3 |
| Molecular Weight | 282.655 |
| Flash Point | 247.7±28.7 °C |
| Exact Mass | 282.020752 |
| PSA | 72.19000 |
| LogP | 1.39 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.692 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2933990090 |
|
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100361-18-0 |
| Literature: Karoli, Tomislav; Mamidyala, Sreeman K.; Zuegg, Johannes; Fry, Scott R.; Tee, Ernest H.L.; Bradford, Tanya A.; Madala, Praveen K.; Huang, Johnny X.; Ramu, Soumya; Butler, Mark S.; Cooper, Matthew A. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2428 - 2433 |
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| Literature: US5281612 A1, ; |
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100361-18-0 |
| Literature: US4571396 A1, ; |
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100361-18-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 45, # 25 p. 5564 - 5575 |
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100361-18-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 45, # 25 p. 5564 - 5575 |
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100361-18-0 |
| Literature: Journal of Medicinal Chemistry, , vol. 36, # 7 p. 871 - 882 |
| Precursor 5 | |
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| DownStream 3 | |
![1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid structure](https://image.chemsrc.com/caspic/331/113533-65-6.png)
![1-cyclopropyl-6-fluoro-7-[(3S)-3-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid structure](https://image.chemsrc.com/caspic/477/122536-91-8.png)
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |