105102-22-5

105102-22-5 structure

Name: Mometasone
Chemical Name: mometasone
CAS Number: 105102-22-5
Molecular Formula: C₂₂H₂₈Cl₂O₄
Molecular Weight: 427.4
Catalog: API Hormone and endocrine-regulating drugs Adrenal corticosteroids
Create Date: 2018-06-27 14:46:45
Modify Date: 2026-06-30 19:33:15
Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis[1][2].

Name	mometasone
Synonyms	Mometasone furoate impurity GQ: What is Mometasone furoate impurity G Q: What is the CAS Number of Mometasone furoate impurity G Q: What is the storage condition of Mometasone furoate impurity G Q: What e the applications of Mometasone furoate impurity G Mometasone Furoate Impurity G/Mometasone MFCD02683426 Mometasone Furoate Impurity 6 Mometasone //BP Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11β,16α) MometasoneFuroateBase MoMetasone (MoMetasone Furoate IMpurity G) Mometasone IMpurity Mometason Furoate Impurity G Pregna-1,4-diene-3,20-dione,9,21-dichloro-11,17-dihydroxy-16-methyl-,(11b,16a)-(9CI) Elocon MOMETOSONE FUROATE Mometaxone analogue 1 MoMetasone Furoate { CreaM} 9a,21-dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione (11β,16α)-9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione Mometasone Impurity G Mometasone Furoate Impurity 7(Mometasone Furoate Impurity G) (8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-triMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one Mometasone Furoate Impurity S iciins Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11b,16a)- (9CI) 9,21-Dichloro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione (Mometasone) MOMETASONE Mometasone 105-5 Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.) 1, 4-PREGNADIEN-9α, 21-DICHLORO-16α-METHYL-11β, 17α-DIOL-3, 20-DIONE Mometasone Furoate Impurity G Momentasone imp. G

Description	Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis[1][2].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
In Vivo	Mometasone (0.1-3 mg/kg; intranasally) inhibits the increased airway sensitivity to aerosolized methacholine at the highest dose tested of 3 mg/kg, and dose-dependently inhibits the allergen-induced increase in Penh in a mouse model of allergic lung inflammation[3].
References	[1]. Veien NK, et al. Long-term, intermittent treatment of chronic hand eczema with mometasone furoate. Br J Dermatol. 1999 May;140(5):882-6. [2]. Lazarus SC, et al. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 May 23;380(21):2009-2019. [3]. Wyss D, et al. Synergistic effect of formoterol and mometasone in a mouse model of allergic lung inflammation. Br J Pharmacol. 2007 Sep;152(1):83-90.

Density	1.35g/cm3
Boiling Point	586.6ºC at 760mmHg
Melting Point	220ºC (decomposes)
Molecular Formula	C₂₂H₂₈Cl₂O₄
Molecular Weight	427.4
Flash Point	308.5ºC
Exact Mass	426.1364648
PSA	93.81000
LogP	4.86920
Vapour Pressure	4.47E-18mmHg at 25°C
Index of Refraction	1.603

83881-08-7

~84%

105102-22-5

Literature: Draper, Richard W.; Bin, Hu; McPhail, Andrew T.; Puar, Mohindar S.; Vater, Eugene J.; Weber, Lois Tetrahedron, 1999 , vol. 55, # 11 p. 3355 - 3364

24916-90-3

105102-22-5

Literature: Tetrahedron, , vol. 55, # 11 p. 3355 - 3364

Precursor 2
83881-08-7 24916-90-3
DownStream 0

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