Name | antimycin a1 |
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Synonyms |
dihydrosamidin
Antimycin A1 (2R,3S,6S,7R,8R)-3-[(3-Formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate Isovaleric Acid 8-Ester with 3-Formamide-N-(7-hexyl-8-hydroxy-4,9-dimethyl-2,6-dioxo-1,5-dioxonan-3-yl)salicylamide Antimycin A |
Description | Antimycin A1 is a specific electron transfer inhibitor of ubiquinol-cytochrome c oxidoreductase. Antimycin A1 inhibits angiogenesis through decrease in VEGF production caused by inhibition of HIF-1α activation[1][2]. |
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Related Catalog | |
In Vitro | Antimycin A, a mixture of Antimycins A1, A2, A3, and A4, is an antibiotic produced by Streptomyces species and displays antifungal, insecticidal, nematocidal, and piscicidal properties[3]. Antimycin A inhibits Bcl-2 and Bcl-xL proteins, inducing apoptosis[4]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 757.9±60.0 °C at 760 mmHg |
Melting Point | 139-140ºC |
Molecular Formula | C28H40N2O9 |
Molecular Weight | 548.625 |
Flash Point | 412.1±32.9 °C |
Exact Mass | 548.273376 |
PSA | 157.33000 |
LogP | 4.68 |
Vapour Pressure | 0.0±2.6 mmHg at 25°C |
Index of Refraction | 1.545 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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