Name | b 581 |
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Synonyms |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-sulfanylpropyl]amino]-3-methylbutyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid
B581 |
Description | Ftase inhibitor I (B581) is a potent, selective and peptidomimetic farnesyl transferase (FTase) inhibitor. Ftase inhibitor I shows selectivity for FTase over geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras)[1]. |
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Related Catalog | |
In Vitro | Ftase inhibitor I (B581) inhibits the ability of only Ras-F-transformed cells, but not geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras)- (or Raf-) transformed cells, to grow in soft agar[1]. |
References |
Density | 1.161g/cm3 |
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Boiling Point | 716.1ºC at 760mmHg |
Molecular Formula | C22H38N4O3S2 |
Molecular Weight | 470.69 |
Flash Point | 386.9ºC |
Exact Mass | 470.23900 |
PSA | 180.58000 |
LogP | 3.25410 |
Appearance | solid | white |
Vapour Pressure | 1.6E-21mmHg at 25°C |
Index of Refraction | 1.566 |
Storage condition | −20°C |
Water Solubility | H2O: soluble |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |