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22264-50-2

22264-50-2 structure
22264-50-2 structure

Name 1-Aminocyclobutanecarboxylic acid
Synonyms N-Methylquipazine dimaleate
1-amino-cyclobutanecarboxylicaci
ACBC-OH
MFCD00661068
cb1700
AC4C-OH
Cyclobutanecarboxylic acid, 1-amino-
1-Aminocyclobutaneca
1-Amino-1-carboxycyclobutane
1-Amino-1-cyclobutanecarboxylic acid
1-aminocyclobutane-1-carboxylic acid
1,1-ACCB
1-Aminocyclobutanecarboxylic acid
1-Aminocyclobutan-1-carboxylic acid
aminocyclobutane carboxylic acid
ACBC
Description 1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1[1].
Related Catalog
References

[1]. Atsushi Inanobe, et al. Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron. 2005 Jul 7;47(1):71-84.

Density 1.3±0.1 g/cm3
Boiling Point 241.1±23.0 °C at 760 mmHg
Melting Point 261ºC (dec.)
Molecular Formula C5H9NO2
Molecular Weight 115.131
Flash Point 99.6±22.6 °C
Exact Mass 115.063332
PSA 63.32000
LogP -0.62
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.540
Storage condition Store at RT

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GU1336000
CHEMICAL NAME :
Cyclobutanecarboxylic acid, 1-amino-
CAS REGISTRY NUMBER :
22264-50-2
BEILSTEIN REFERENCE NO. :
2802253
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H9-N-O2
MOLECULAR WEIGHT :
115.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS GU1336000
HS Code 2922499990

~70%

22264-50-2 structure

22264-50-2

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2005/19158 A1, 2005 ; Location in patent: Page/Page column 18 ;

~40%

22264-50-2 structure

22264-50-2

Literature: Pirrung; Cao; Chen Journal of Organic Chemistry, 1995 , vol. 60, # 18 p. 5790 - 5794

~76%

22264-50-2 structure

22264-50-2

Literature: Gaoni, Yehiel Organic Preparations and Procedures International, 1995 , vol. 27, # 2 p. 185 - 212


HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%