Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5H-Pyrimido[4,5-d]thiazolo[3,2-a]pyrimidine-8-ethanol,2,7-dimethyl-
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92-35-3

92-35-3 structure

Name: Thiochrome
Chemical Name: Thiochrome
CAS Number: 92-35-3
Molecular Formula: C₁₂H₁₄N₄OS
Molecular Weight: 262.33100
Catalog: analytical chemistry Standard Analytical standard
Create Date: 2018-04-19 08:00:00
Modify Date: 2024-01-02 20:51:41
Thiochrome, a natural oxidation product and metabolite of thiamine, is a selective M4 muscarinic receptor of acetylcholine (ACh) affinity enhancer. Thiochrome has neutral cooperativity with ACh at M1 to M3 receptors[1][2].

Name	Thiochrome
Synonyms	2-(2,7-dimethyl-5H-pyrimido[4,5-d]thiazolo[3,2-a]pyrimidin-8-yl)-ethanol 2-(2,7-Dimethyl-5H-pyrimido[4,5-d]thiazolo[3,2-a]pyrimidin-8-yl)-aethanol 2-(2,7-dimethyl-5H-thiazolo[3',2':1,2]pyrimido[4,5-d]pyrimidin-8-yl)ethanol 2-{6,12-dimethyl-4-thia-2,7,11,13-tetraazatricyclo[7.4.0.0^{3,7}]trideca-1(13),2,5,9,11-pentaen-5-yl}ethan-1-ol 5H-Pyrimido(4,5-d)thiazolo(3,2-a)pyrimidine-8-ethanol,2,7-dimethyl T7891_FLUKA EINECS 202-149-9 2,7-dimethyl-5H-pyrimido[4,5-d]thiazolo[3,2-a]pyrimidine-8-ethanol 2,7-Dimethylthiachromine-8-ethanol 5H-PYRIMIDO(4,5-D)THIAZOLO(3,2-A)PYRIMIDINE-8-ETHANOL, 2,7-DIMETHYL- THIOCHROME Thiachrome MFCD00010519 TETRAKIS(2-ETHYLBUTYL)SILICATE

Description	Thiochrome, a natural oxidation product and metabolite of thiamine, is a selective M4 muscarinic receptor of acetylcholine (ACh) affinity enhancer. Thiochrome has neutral cooperativity with ACh at M1 to M3 receptors[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Metabolic Disease
In Vivo	Thiochrome can increase the intensity of the reproduction process of the representatives of one-cell organisms worms, crustaceans, insects and fishes[1].
References	[1]. Petrov SA, et al. Administration of Thiamine and Thiochrome Enhanced Reproduction of Chlorella, Drosophila melanogaster, and Danio. J Nutr Sci Vitaminol (Tokyo). 2016;62(1):6-11. [2]. Lazareno S, et al. Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity. Mol Pharmacol. 2004 Jan;65(1):257-66.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%