Name | 3-Methyl-2-oxobutanoic acid, sodium salt |
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Synonyms |
Butanoic acid, 3-methyl-2-oxo-, sodium salt (1:1)
MFCD00002581 EINECS 223-062-2 sodium,3-methyl-2-oxobutanoate Butanoic acid, 3-methyl-2-oxo-, sodium salt Sodium 3-methyl-2-oxobutanoate 3-Methyl-2-oxobutanoic acid |
Description | Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[1][2][3]. |
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Related Catalog | |
In Vitro | Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) is a precursor of pantothenic acid in Escherichia coli[1]. Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) enhances alpha-ketoisocaproic acid and alpha-keto-beta-methyl-n-valeric acid, but diminishes the corresponding amino acids, and causes an early decline of ornithine along with a late augmentation of plasma arginine[2]. |
In Vivo | Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) induces convulsions through GABAergic and glutamatergic mechanisms in rats[3]. |
References |
Boiling Point | 170.2ºC at 760 mmHg |
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Melting Point | 220-230 °C (dec.)(lit.) |
Molecular Formula | C5H7NaO3 |
Molecular Weight | 138.097 |
Exact Mass | 138.029282 |
PSA | 57.20000 |
Storage condition | Store at 0-5°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Safety Phrases | S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2904909090 |
~% 3715-29-5 |
Literature: MERCK and CO., INC. Patent: WO2005/118529 A2, 2005 ; Location in patent: Page/Page column 26 ; |
~% 3715-29-5 |
Literature: Fizet Helvetica Chimica Acta, 1982 , vol. 65, # 7 p. 2024 - 2028 |
Precursor 3 | |
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DownStream 10 | |
HS Code | 2918300090 |
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Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |