Sodium 3-methyl-2-oxobutanoate

Modify Date: 2024-01-03 16:46:31

Sodium 3-methyl-2-oxobutanoate structure	Common Name	Sodium 3-methyl-2-oxobutanoate
	CAS Number	3715-29-5	Molecular Weight	138.097
	Density	N/A	Boiling Point	170.2ºC at 760 mmHg
	Molecular Formula	C₅H₇NaO₃	Melting Point	220-230 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	N/A

Use of Sodium 3-methyl-2-oxobutanoate

Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[1][2][3].

Name	3-Methyl-2-oxobutanoic acid, sodium salt
Synonym	More Synonyms

Description	Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[1][2][3].
Related Catalog	Research Areas >> Others
In Vitro	Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) is a precursor of pantothenic acid in Escherichia coli[1]. Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) enhances alpha-ketoisocaproic acid and alpha-keto-beta-methyl-n-valeric acid, but diminishes the corresponding amino acids, and causes an early decline of ornithine along with a late augmentation of plasma arginine[2].
In Vivo	Sodium 3-methyl-2-oxobutanoate (alpha-Ketoisovaleric acid) induces convulsions through GABAergic and glutamatergic mechanisms in rats[3].
References	[1]. MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65(4):388-93. [2]. Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr;103(4):597-605. [3]. Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9;894(1):68-73.

Boiling Point	170.2ºC at 760 mmHg
Melting Point	220-230 °C (dec.)(lit.)
Molecular Formula	C₅H₇NaO₃
Molecular Weight	138.097
Exact Mass	138.029282
PSA	57.20000
Storage condition	Store at 0-5°C

Sodium 3-methyl-2-oxobutanoate MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2904909090

Ethyl 3-methyl-...

CAS#:20201-24-5

Sodium 3-methyl...

CAS#:3715-29-5

Literature: MERCK and CO., INC. Patent: WO2005/118529 A2, 2005 ; Location in patent: Page/Page column 26 ;

ISOPROPYLMAGNES...

CAS#:1068-55-9

Diethyloxalate

CAS#:95-92-1

Sodium 3-methyl...

CAS#:3715-29-5

Literature: Fizet Helvetica Chimica Acta, 1982 , vol. 65, # 7 p. 2024 - 2028

Precursor 3
CAS#:20201-24-5 Ethyl 3-methyl-... CAS#:1068-55-9 ISOPROPYLMAGNES... CAS#:95-92-1 Diethyloxalate
DownStream 10
CAS#:3952-67-8 methyl 3-methyl... CAS#:59935-29-4 L-Valine-15N CAS#:72-18-4 L-Valine CAS#:640-68-6 H-D-Val-OH
CAS#:759-05-7 α-Ketoisovaleri... CAS#:13031-04-4 4,4-Dimethyldih... CAS#:79-50-5 DL-Pantolactone CAS#:76585-78-9 benzyl 3-methyl...
CAS#:77257-02-4 D-[2-2H]valine CAS#:77257-03-5 l-valine-2-d1

HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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Butanoic acid, 3-methyl-2-oxo-, sodium salt (1:1)

MFCD00002581

EINECS 223-062-2

sodium,3-methyl-2-oxobutanoate

Butanoic acid, 3-methyl-2-oxo-, sodium salt

Sodium 3-methyl-2-oxobutanoate

3-Methyl-2-oxobutanoic acid