301326-22-7
301326-22-7 structure
- Name: CH-223191
- Chemical Name: 2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
- CAS Number: 301326-22-7
- Molecular Formula: C19H19N5O
- Molecular Weight: 333.387
- Catalog: Biochemical Inhibitor Metabolism AhR antagonist
- Create Date: 2016-04-13 03:47:24
- Modify Date: 2025-08-28 11:24:28
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CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR). CH-223191 blocks the binding of TCDD to AhR with an IC50 of 0.03 µM.
| Name | 2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide |
|---|---|
| Synonyms |
2-Methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide UNII-HYE7315Z4C 1H-Pyrazole-5-carboxamide, 1-methyl-N-[2-methyl-4-[(E)-2-(2-methylphenyl)diazenyl]phenyl]- 1-Methyl-N-{2-methyl-4-[(E)-(2-methylphenyl)diazenyl]phenyl}-1H-pyrazole-5-carboxamide AhR Antagonist CH-223191 |
| Description | CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR). CH-223191 blocks the binding of TCDD to AhR with an IC50 of 0.03 µM. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 469.4±45.0 °C at 760 mmHg |
| Molecular Formula | C19H19N5O |
| Molecular Weight | 333.387 |
| Flash Point | 237.7±28.7 °C |
| Exact Mass | 333.158966 |
| PSA | 75.13000 |
| LogP | 3.48 |
| Appearance | orange-brown |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.633 |
| Storage condition | Store at +4°C |
| Water Solubility | DMSO: ≥20mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| Safety Phrases | 22 |
| RIDADR | NONH for all modes of transport |