760-78-1
760-78-1 structure
- Name: DL-Norvaline
- Chemical Name: 2-aminopentanoic acid
- CAS Number: 760-78-1
- Molecular Formula: C5H11NO2
- Molecular Weight: 117.146
- Catalog: Biochemical Amino acids and their derivatives Proline derivatives
- Create Date: 2018-08-03 17:23:20
- Modify Date: 2026-07-03 12:44:27
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DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.
| Name | 2-aminopentanoic acid |
|---|---|
| Synonyms |
DL-NORVALINE
DL-alpha-Aminovaleric acid Dl-n-valine α-DL-Aminopentanoic acid DL-2-Aminovaleric acid (T) a-DL-Aminopentanoic acid NORVALINE, DL 2-AMINOPENTANOIC ACID DL-2-AMINOVALERIC ACID a-Aminovaleric Acid 2-Aminopentanoic acid EINECS 212-082-7 (n)-2-aminopentanoic acid DL-α-Aminovaleric acid H-DL-Nva-OH H-DL-L-Norvaline UNII:V639KTF2SZ Norvaline (VAN) DL-ALPHA-AMINO-N-VALERICACID 2-Aminovaleric acid DL-NORVAALINE DL-2-Aminopentanoic acid (2R)-2-ammoniopentanoate H-DL-Nval-OH (+/-)-2-AMINOPENTANOIC ACID DL-Norvaline //BP α-DL-aminopentanoicacid dextro,laevo-norvaline MFCD00064420 alpha-DL-Aminopentanoic acid DL-Norvaline> (R,S)-2-aminopentanoic acid 2-aminopentanoicaci DL-A-AMINO-N-VALERIC ACID (±)-2-Aminopentanoic acid DL-NORVALINE SIGMA ADE H-DL-Nva-OH rac-norvaline Dl-n-valine English name: DL-Norvaline aminovaleric acid 2-aminopentanoic acid(-1) dl-alpha-Amino-N-valenic acid H-DL-NVA-OH D-Norvaline/L-norvaline,(1:1) DL-2-Aminovaleric Acid DL-norVal-OH DL -Norvaline DL-2-AMINOPENTANOIC ACID DL-Norvaline (HPLC) rac-(2R*)-2-Aminopentanoic acid APE Norvaline NVA Valeric acid, 2-amino-, DL NORVALINE, DL-(RG) (±)-Norvaline |
| Description | DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | DL-Norvaline, a derivative of L-norvaline[1], L-norvaline is a non-competitive inhibitor of arginase[2]. |
| Cell Assay | A murine macrophage cell line (RAW264.7) is used throughout the study, RAW264.7 cells are induced by A. actinomycetemcomitans-lipopolysaccharide, cells are incubated with various concentrations of L-norvaline or DL-norvaline (0.01, 0.1, 1, 10 mM) and 10 μg of A. actinomycetemcomitans-lipopolysaccharide. In other experiments, cells are incubated with antimurine CD14 or antimurine toll-like receptor 2 and 4 antibody at room temperature for 1 h, washed three times, and then stimulated with 10 μg of A. actinomycetemcomitans-lipopolysaccharide. All experiments are repeated three times, each consisting of triplicate cultures[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 222.9±23.0 °C at 760 mmHg |
| Melting Point | ≥300 °C (dec.) |
| Molecular Formula | C5H11NO2 |
| Molecular Weight | 117.146 |
| Flash Point | 88.6±22.6 °C |
| Exact Mass | 117.078979 |
| PSA | 63.32000 |
| LogP | 0.38 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.464 |
| Storage condition | Store at RT. |
| Water Solubility | 1 g/10 mL (18 ºC) |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| Risk Phrases | R20/21/22 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29224995 |
| Precursor 9 | |
|---|---|
| DownStream 10 | |
| HS Code | 29224995 |
|---|