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89-73-6

89-73-6 structure
89-73-6 structure

Name salicylhydroxamic acid
Synonyms EINECS 201-934-3
N,2-dihydroxybenzamide
MFCD00002110
Salicylhydroxamic acid
Density 1.4±0.1 g/cm3
Melting Point 177 °C (dec.)(lit.)
Molecular Formula C7H7NO3
Molecular Weight 153.135
Flash Point 248.9ºC
Exact Mass 153.042587
PSA 69.56000
LogP 0.53
Index of Refraction 1.626
Stability Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VO6870000
CHEMICAL NAME :
Salicylohydroxamic acid
CAS REGISTRY NUMBER :
89-73-6
LAST UPDATED :
199412
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C7-H7-N-O3
MOLECULAR WEIGHT :
153.15
WISWESSER LINE NOTATION :
QMVR BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
860 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
1 mmol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 29,1275,1980
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H312-H315-H319-H332-H335-H351
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful;
Risk Phrases R40
Safety Phrases S22-S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS VO6870000
HS Code 2924299090

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Literature: JANSSEN PHARMACEUTICA N.V. Patent: WO2005/89753 A2, 2005 ; Location in patent: Page/Page column 27 ;

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Literature: Lienard, Benoit M.R.; Horsfall, Louise E.; Galleni, Moreno; Frere, Jean-Marie; Schofield, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 4 p. 964 - 968

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Literature: EP1308439 A1, ;

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Literature: Oriental Journal of Chemistry, , vol. 28, # 4 p. 1841 - 1844

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Literature: Bulletin de la Societe Chimique de France, , p. 2573 - 2580

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89-73-6

Literature: Chemicke Listy, , vol. 45, p. 461 Chem.Abstr., , p. 7543

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Literature: Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <5> 17 II, p. 364 Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <5>18 I, p. 378 Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <5> 18 I, p. 222
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%