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25077-25-2

25077-25-2 structure
25077-25-2 structure
  • Name: 1-Methyl-2,6-piperidinedione
  • Chemical Name: 1-methylpiperidine-2,6-dione
  • CAS Number: 25077-25-2
  • Molecular Formula: C6H9NO2
  • Molecular Weight: 127.141
  • Create Date: 2016-11-08 01:29:32
  • Modify Date: 2024-01-10 12:03:18

Name 1-methylpiperidine-2,6-dione
Synonyms N-Methylglutarimid
N-Methylglutarimide
Glutarimide,N-methyl
N-methyladipinimide
1-Methylpiperidine-2,6-dione
1-methyl-piperidine-2,6-dione
N-methylglutaramide
2,6-Piperidinedione,1-methyl
2,6-Piperidinedione, 1-methyl-
1-Methylglutarimide
1-Methyl-2,6-piperidinedione
Density 1.2±0.1 g/cm3
Boiling Point 243.8±9.0 °C at 760 mmHg
Melting Point 30-31°C
Molecular Formula C6H9NO2
Molecular Weight 127.141
Flash Point 110.7±11.1 °C
Exact Mass 127.063332
PSA 37.38000
LogP 0.35
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.484

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA5220000
CHEMICAL NAME :
Glutarimide, N-methyl-
CAS REGISTRY NUMBER :
25077-25-2
BEILSTEIN REFERENCE NO. :
0116172
LAST UPDATED :
199710
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H9-N-O2
MOLECULAR WEIGHT :
127.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3400 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571226
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>512 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 173,115,1968
Hazard Codes Xi

~92%

25077-25-2 structure

25077-25-2

Literature: Yoshifuji, Shigeyuki; Arakawa, Yukimi; Nitta, Yoshihiro Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 1 p. 357 - 363

~98%

25077-25-2 structure

25077-25-2

Literature: Marson; Khan; Porter Journal of Organic Chemistry, 2001 , vol. 66, # 14 p. 4771 - 4775

~%

25077-25-2 structure

25077-25-2

Literature: Lukes; Smetackova Collection of Czechoslovak Chemical Communications, 1933 , vol. 5, p. 61,64 Full Text Show Details Hall et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 6420,6421

~%

25077-25-2 structure

25077-25-2

Literature: Iley, Jim; Tolando, Roberto; Constantino, Luis Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 8 p. 1299 - 1305

~%

25077-25-2 structure

25077-25-2

Literature: Irrera Gazzetta Chimica Italiana, 1935 , vol. 65, p. 464

~%

25077-25-2 structure

25077-25-2

Literature: Ozawa, Naganori; Nakajima, Setsuko; Zaoya, Kyoko; Hamaguchi, Fumiko; Nagasaka, Tatsuo Heterocycles, 1991 , vol. 32, # 5 p. 889 - 894