1-Methyl-2,6-piperidinedione

Modify Date: 2024-01-10 12:03:18

1-Methyl-2,6-piperidinedione structure	Common Name	1-Methyl-2,6-piperidinedione
	CAS Number	25077-25-2	Molecular Weight	127.141
	Density	1.2±0.1 g/cm3	Boiling Point	243.8±9.0 °C at 760 mmHg
	Molecular Formula	C₆H₉NO₂	Melting Point	30-31°C
	MSDS	N/A	Flash Point	110.7±11.1 °C

Name	1-methylpiperidine-2,6-dione
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	243.8±9.0 °C at 760 mmHg
Melting Point	30-31°C
Molecular Formula	C₆H₉NO₂
Molecular Weight	127.141
Flash Point	110.7±11.1 °C
Exact Mass	127.063332
PSA	37.38000
LogP	0.35
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.484

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA5220000

CHEMICAL NAME :: Glutarimide, N-methyl-

CAS REGISTRY NUMBER :: 25077-25-2

BEILSTEIN REFERENCE NO. :: 0116172

LAST UPDATED :: 199710

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H9-N-O2

MOLECULAR WEIGHT :: 127.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3400 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571226

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >512 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 173,115,1968

Hazard Codes	Xi

2-Piperidinone,...

CAS#:931-20-4

~92%

1-Methyl-2,6-pi...

CAS#:25077-25-2

Literature: Yoshifuji, Shigeyuki; Arakawa, Yukimi; Nitta, Yoshihiro Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 1 p. 357 - 363

Glutarimide

CAS#:1121-89-7

methyl iodide

CAS#:74-88-4

~98%

1-Methyl-2,6-pi...

CAS#:25077-25-2

Literature: Marson; Khan; Porter Journal of Organic Chemistry, 2001 , vol. 66, # 14 p. 4771 - 4775

Glutaric acid

CAS#:110-94-1

methylamine

CAS#:74-89-5

1-Methyl-2,6-pi...

CAS#:25077-25-2

N1,N5-Dimethylp...

CAS#:56269-42-2

Literature: Lukes; Smetackova Collection of Czechoslovak Chemical Communications, 1933 , vol. 5, p. 61,64 Full Text Show Details Hall et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 6420,6421

2-Piperidinone,...

CAS#:931-20-4

2-Piperidone

CAS#:675-20-7

Glutarimide

CAS#:1121-89-7

1-Methyl-2,6-pi...

CAS#:25077-25-2

Literature: Iley, Jim; Tolando, Roberto; Constantino, Luis Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 8 p. 1299 - 1305

diazomethane

CAS#:186581-53-3

Glutarimide

CAS#:1121-89-7

1-Methyl-2,6-pi...

CAS#:25077-25-2

Literature: Irrera Gazzetta Chimica Italiana, 1935 , vol. 65, p. 464

Glutaric acid

CAS#:110-94-1

methylamine

CAS#:74-89-5

1-Methyl-2,6-pi...

CAS#:25077-25-2

Literature: Ozawa, Naganori; Nakajima, Setsuko; Zaoya, Kyoko; Hamaguchi, Fumiko; Nagasaka, Tatsuo Heterocycles, 1991 , vol. 32, # 5 p. 889 - 894

Precursor 6
CAS#:931-20-4 2-Piperidinone,... CAS#:1121-89-7 Glutarimide CAS#:74-88-4 methyl iodide CAS#:110-94-1 Glutaric acid
CAS#:74-89-5 methylamine CAS#:186581-53-3 diazomethane
DownStream 10
CAS#:111725-60-1 3-(dimethylamin... CAS#:506-48-9 Octacosanoic Acid CAS#:506-46-7 Cerotic acid CAS#:506-12-7 Margaric acid
CAS#:626-67-5 1-Methylpiperidine CAS#:143-07-7 Lauric acid CAS#:2424-90-0 Heptadecanedioi... CAS#:871-70-5 Octadecanedioic acid
CAS#:931-20-4 2-Piperidinone,... CAS#:544-63-8 Myristic acid