578-76-7

578-76-7 structure

Name: 7-Methylguanine
Chemical Name: 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one
CAS Number: 578-76-7
Molecular Formula: C₆H₇N₅O
Molecular Weight: 165.153
Catalog: Biochemical Nucleoside drugs Nucleotides and their analogues
Create Date: 2018-08-26 15:38:12
Modify Date: 2025-08-25 12:26:34
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method.

Name	2-amino-7-methyl-1,7-dihydro-6H-purin-6-one
Synonyms	6H-Purin-6-one, 2-amino-1,7-dihydro-7-methyl- 2-amino-7-methyl-3H-purin-6-one 2-Amino-7-methyl-1,7-dihydro-6H-purin-6-one 7-methyl-Guanine (8CI) 7-N-methylguanine N(sup 7)-Methylguanine 7-methyl-Guanine Epiguanine 2-Amino-7-methylhypoxanthine N7-Methylguanine 7-Methylguanine 2-amino-7-methyl-1,7-dihydro-purin-6-one 2-Amino-1,7-dihydro-7-methyl-6H-purin-6-one GUANINE,7-METHYL 2-Amino-6-hydroxy-7-methylpurine

Description	7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method.
Related Catalog	Natural Products >> Others Research Areas >> Others
Target	Human Endogenous Metabolite
References	[1]. Lee S, et al. Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J Am Chem Soc. 2008 Sep 3;130(35):11570-1.

REFERENCE :: ZAPOAK Zeitschrift fuer Allgemeine Mikrobiologie. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086 Ger. Dem. Rep.) V.1- 1960- Volume(issue)/page/year: 12,583,1972