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2764-03-6

2764-03-6 structure

2764-03-6 structure

Name: N-[(9Z,12Z)-9,12-Octadecadienoyl]glycine
Chemical Name: Linoleoyl Glycine
CAS Number: 2764-03-6
Molecular Formula: C₂₀H₃₅NO₃
Molecular Weight: 337.497
Create Date: 2017-06-23 06:59:55
Modify Date: 2025-08-25 18:14:22
Linoleoyl glycine is a modified polyunsaturated fatty acid. Linoleoyl glycine has activating effects on human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in Xenopus oocytes[1].

Name	Linoleoyl Glycine
Synonyms	Glycine-linoleamide Glycine, N-[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]- N-[(9Z,12Z)-9,12-Octadecadienoyl]glycine N-linoleoyl glycine N-[(9Z,12Z)-octadeca-9,12-dienoyl]glycine linoleyl glycine Linoleoyl-glycin

Description	Linoleoyl glycine is a modified polyunsaturated fatty acid. Linoleoyl glycine has activating effects on human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in Xenopus oocytes[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Skarsfeldt MA, et al. Polyunsaturated fatty acid-derived IKs channel activators shorten the QT interval ex-vivo and in-vivo. Acta Physiol (Oxf). 2020;229(4):e13471.

Density	1.0±0.1 g/cm3
Boiling Point	530.7±43.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₅NO₃
Molecular Weight	337.497
Flash Point	274.8±28.2 °C
Exact Mass	337.261688
PSA	66.40000
LogP	6.05
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.489
Storage condition	-20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MC0596320

CHEMICAL NAME :: Glycine, N-linoleoyl-

CAS REGISTRY NUMBER :: 2764-03-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H35-N-O3

MOLECULAR WEIGHT :: 337.56

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 44,145,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 44,145,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 44,145,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 44,145,1986

HS Code	2924199090

60-33-3 structure

60-33-3

56-40-6 structure

56-40-6

~%

2764-03-6 structure

2764-03-6

Literature: Dang, Hung The; Kang, Gyeoung Jin; Yoo, Eun Sook; Hong, Jongki; Choi, Jae Sue; Kim, Hyung Sik; Chung, Hae Young; Jung, Jee H. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 4 p. 1520 - 1527

Precursor 2
60-33-3 56-40-6
DownStream 0

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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