60-33-3

60-33-3 structure

Name	linoleic acid
Synonyms	MFCD00064241 cis,cis-9,12-octadecadienoic acid Pamolyn 9,12-Octadecadienoic acid, (9Z,12Z)- FEMA 3380 Hidiene cis-9,cis-12-octadecadienoic acid Linoleic acid LINOLEATE emersol310 unifac6550 EINECS 200-470-9 9-cis,12-cis-Octadecadienoic acid IVELIP (9Z,12Z)-9,12-Octadecadienoic acid cis-Linoleic acid emersol315 Linoleic 9,12-octadecadienoic acid (9Z,12Z)-octadeca-9,12-dienoic acid

Description	Linoleic acid is a critical component of polyunsaturated fatty acids.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Others
Target	Human Endogenous Metabolite
In Vitro	Linoleic acid contains unsaturated double bonds that are highly vulnerable to free radical attack and oxidation. If ROS are produced in great quantities, the body can no longer efficiently remove them. In such instances, ROS may be released into the extracellular space, causing damage to surrounding cells and tissues. Linoleic acid is a decomposition product of a free fatty acid and has been linked to erythrocyte damage[1].
References	[1]. Yuan T, et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. Int J Clin Exp Pathol. 2015 May 1;8(5):5044-52.

Density	0.9±0.1 g/cm3
Boiling Point	360.6±0.0 °C at 760 mmHg
Melting Point	-5 °C
Molecular Formula	C₁₈H₃₂O₂
Molecular Weight	280.445
Flash Point	273.0±14.4 °C
Exact Mass	280.240234
PSA	37.30000
LogP	7.18
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.478
Storage condition	2-8°C
Stability	Stability Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	INSOLUBLE
Freezing Point	-5℃

REFERENCE :: 85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 Volume(issue)/page/year: -,127,1977 ** ACUTE TOXICITY DATA **

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,327,1970

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3728459

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 104,793,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 43040 No. of Facilities: 4852 (estimated) No. of Industries: 61 No. of Occupations: 64 No. of Employees: 45762 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 43040 No. of Facilities: 2186 (estimated) No. of Industries: 26 No. of Occupations: 37 No. of Employees: 57612 (estimated) No. of Female Employees: 16829 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi
Risk Phrases	R36
Safety Phrases	S26-S24/25-S36
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	RF9990000
HS Code	2916150000

HS Code	2916190090
Summary	2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%