96027-74-6
96027-74-6 structure
- Name: Desethyl Amiodarone Hydrochloride
- Chemical Name: (2-butyl-1-benzofuran-3-yl)-[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]methanone,hydrochloride
- CAS Number: 96027-74-6
- Molecular Formula: C23H26ClI2NO3
- Molecular Weight: 653.719
- Catalog: analytical chemistry Standard standard material
- Create Date: 2018-12-27 13:27:26
- Modify Date: 2026-07-01 20:14:42
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Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM[1][2][3].
| Name | (2-butyl-1-benzofuran-3-yl)-[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]methanone,hydrochloride |
|---|---|
| Synonyms |
2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl Ketone Hydrochlorid
desethylamiodarone Amiodone Imp B Amiodone Impurity 2（HCl） Amiodarone Impurity 2 Methanone, (2-butyl-3-benzofuranyl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]-, hydrochloride (1:1) N-Desethylamiodone HCl mono-N-desethylamiodarone hydrochloride Amiodone Impurity B (N-Desethyl Amiodone HCl) N-Desethylamiodone (hydrochloride) (2-Butyl-1-benzofuran-3-yl){4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl}methanone hydrochloride (1:1) 2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl Ketone Hydrochloride Desethyl Amiodone Hydrochloride Amiodone Impurity B (as Hydrochloride) mono-N-desethylamiodone hydrochloride LB 33020 hydrochloride AMiodone IMpurity B Amiodone Desethyl Amiodone Hydrochloride Desethyl Amiodone Hydrochloride D4 Amiodone impurity 2/Amiodone Impurity B HCl/N-Desethyl Amiodone HCl/2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl Ketone Hydrochloride (2-Butylbenzofuran-3-yl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]methanone Hydrochloride (Desethyl Amiodone Impurity 2 Hydrochloride (Amiodone Impurity B Hydrochloride) Desethylamiodone Hydrochloride 1.0 mg/ml in Methanol (as free base) Amiodone Impurity 2 Hydrochloride(Amiodone Impurity B Hydrochloride)(Amiodone Related Compound B G Hydrochloride) Amiodone Impurity B HCl Desethylamiodarone hydrochloride N-Desethylamiodone hydrochloride solution (2-butylbenzofuran-3-yl)(4-(2-(ethylaMino)ethoxy)-3,5-diiodophenyl)Methanone hydrochloride (2-Butylbenzofuran-3-yl)[4-[2-(ethy Amiodone Impurity B HCl (N-Desethyl Amiodone HCl) Amiodone Hydrochloride Impurity B as Hydrochloride Amiodone Impurity BQ: What is Amiodone Impurity B Q: What is the CAS Number of Amiodone Impurity B Q: What is the storage condition of Amiodone Impurity B |
| Description | Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM[1][2][3]. |
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| Related Catalog | |
| References |
| Boiling Point | 630.3ºC at 760 mmHg |
|---|---|
| Melting Point | 176-178ºC |
| Molecular Formula | C23H26ClI2NO3 |
| Molecular Weight | 653.719 |
| Flash Point | 335ºC |
| Exact Mass | 652.969055 |
| PSA | 51.47000 |
| LogP | 7.39680 |
| Storage condition | -20°C Freezer, Under Inert Atmosphere |
| Stability | Moisture Sensitive |
| Symbol |
GHS02, GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H301 + H311 + H331-H370 |
| Precautionary Statements | P210-P260-P280-P301 + P310-P311 |
| Hazard Codes | F,T |
| Risk Phrases | 11-23/24/25-39/23/24/25 |
| Safety Phrases | 7-16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| Precursor 3 | |
|---|---|
| DownStream 0 | |