171596-28-4
171596-28-4 structure
- Name: 6-epi-Tadalafil
- Chemical Name: cis-Tadalafil
- CAS Number: 171596-28-4
- Molecular Formula: C22H19N3O4
- Molecular Weight: 389.40
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2016-11-24 18:06:46
- Modify Date: 2024-01-10 11:02:12
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cis-ent-Tadalafil (Tadalafil EP Impurity C) is a highly potent PDE5 inhibitor with an IC50 value of 5 nM and has blood pressure lowering activity[1].
| Name | cis-Tadalafil |
|---|---|
| Synonyms |
Tadalafil 6S,12ar diastereomer
epi-tadafil UNII-MGY23Z94HY 6-epi-Tadalafil Tadalafil Impurity 11 |
| Description | cis-ent-Tadalafil (Tadalafil EP Impurity C) is a highly potent PDE5 inhibitor with an IC50 value of 5 nM and has blood pressure lowering activity[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.51±0.1 g/cm3 (20 ºC 760 Torr) |
|---|---|
| Melting Point | 290-292 ºC |
| Molecular Formula | C22H19N3O4 |
| Molecular Weight | 389.40 |
| Exact Mass | 389.13800 |
| PSA | 74.87000 |
| LogP | 2.08710 |
| Storage condition | 2-8°C |
| Water Solubility | Insuluble (8.6E-3 g/L) (25 ºC) |
| Precursor 9 | |
|---|---|
| DownStream 0 | |
![methyl (1S,3R)-2-(N-(((9H-fluoren-9-yl)methoxy)carbonyl)-N-methylglycyl)-1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate structure](https://www.chemsrc.com/caspic/359/749864-19-5.png)
![methyl (1S,3R)-1-(1,3-benzodioxol-5-yl)-3-(2-chloroacetyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate structure](https://www.chemsrc.com/caspic/090/629652-40-0.png)
![methyl (1S,3R)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate structure](https://www.chemsrc.com/caspic/205/171596-42-2.png)
