Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Oryzalin
Price: ￥538.0/100mg ￥368.0/250mg ￥1078.0/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

19044-88-3

19044-88-3 structure

Name: Oryzalin
Chemical Name: oryzalin
CAS Number: 19044-88-3
Molecular Formula: C₁₂H₁₈N₄O₆S
Molecular Weight: 346.36000
Catalog: Chemical pesticide herbicide Other herbicides
Create Date: 2018-05-17 08:00:00
Modify Date: 2024-01-03 02:27:05
Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle[1].

Name	oryzalin
Synonyms	4-(dipropylamino)-3,5-dinitrobenzene-1-sulfonamide Surflan Caswell No. 623A 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide Ryzelan MFCD00078725 3,5-dinitro-N4,N4-dipropylsulfanilamide Dirimal ORYZALIN 3,5-Dinitro-4-dipropylamino-benzenesulphonamide Dinitrodipropylsulfanilamide Dirimal Extra 3,5-dinitro-N',N'-dipropylsulfanilamide EINECS 242-777-0

Description	Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Morejohn LC, et al. Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro. Planta. 1987 Oct;172(2):252-64.

Density	1.2
Boiling Point	514ºC at 760mmHg
Melting Point	141°C
Molecular Formula	C₁₂H₁₈N₄O₆S
Molecular Weight	346.36000
Flash Point	264.6ºC
Exact Mass	346.09500
PSA	163.42000
LogP	4.60430
Vapour Pressure	1.13E-10mmHg at 25°C
Index of Refraction	1.588

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WO9350000

CHEMICAL NAME :: Sulfanilamide, 3,5-dinitro-N(sup 4),N(sup 4)-dipropyl-

CAS REGISTRY NUMBER :: 19044-88-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C12-H18-N4-O6-S

MOLECULAR WEIGHT :: 346.40

WISWESSER LINE NOTATION :: ZSWR CNW ENW DN3&3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10000 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - gerbil

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 300 ug/plate

REFERENCE :: KHFKDF K'o Hsueh Fa Chan Yueh K'an. Progress in Sciences. (Kuo Chia K'o Hsueh Wei Yuan Hui, 2 Canton St., Taipei 107, Taiwan) V.1- 1973- Volume(issue)/page/year: 8,551,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	N:Dangerousfortheenvironment;
Risk Phrases	R51/53
Safety Phrases	S60
RIDADR	UN 3077
RTECS	WO9350000
HS Code	2935009017

37851-36-8

19044-88-3

Literature: Bioorganic and medicinal chemistry letters, , vol. 12, # 17 p. 2395 - 2398

142-84-7

19044-88-3

Literature: Journal of Medicinal Chemistry, , vol. 47, # 7 p. 1823 - 1832

38185-06-7

19044-88-3

Literature: Journal of Medicinal Chemistry, , vol. 47, # 7 p. 1823 - 1832

88-91-5

19044-88-3

Literature: Bioorganic and medicinal chemistry letters, , vol. 12, # 17 p. 2395 - 2398

62443-96-3

19044-88-3

Literature: Bioorganic and medicinal chemistry letters, , vol. 12, # 17 p. 2395 - 2398

HS Code	2935009017
Summary	2935009017 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%