Oryzalin

Modify Date: 2025-08-21 11:20:30

Oryzalin structure	Common Name	Oryzalin
	CAS Number	19044-88-3	Molecular Weight	346.36000
	Density	1.2	Boiling Point	514ºC at 760mmHg
	Molecular Formula	C₁₂H₁₈N₄O₆S	Melting Point	141°C
	MSDS	Chinese USA	Flash Point	264.6ºC

Use of Oryzalin

Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle[1].

Name	oryzalin
Synonym	More Synonyms

Description	Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Morejohn LC, et al. Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro. Planta. 1987 Oct;172(2):252-64.

Density	1.2
Boiling Point	514ºC at 760mmHg
Melting Point	141°C
Molecular Formula	C₁₂H₁₈N₄O₆S
Molecular Weight	346.36000
Flash Point	264.6ºC
Exact Mass	346.09500
PSA	163.42000
LogP	4.60430
Vapour Pressure	1.13E-10mmHg at 25°C
Index of Refraction	1.588
InChIKey	UNAHYJYOSSSJHH-UHFFFAOYSA-N
SMILES	CCCN(CCC)c1c([N+](=O)[O-])cc(S(N)(=O)=O)cc1[N+](=O)[O-]

Oryzalin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WO9350000

CHEMICAL NAME :: Sulfanilamide, 3,5-dinitro-N(sup 4),N(sup 4)-dipropyl-

CAS REGISTRY NUMBER :: 19044-88-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C12-H18-N4-O6-S

MOLECULAR WEIGHT :: 346.40

WISWESSER LINE NOTATION :: ZSWR CNW ENW DN3&3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10000 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - gerbil

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 300 ug/plate

REFERENCE :: KHFKDF K'o Hsueh Fa Chan Yueh K'an. Progress in Sciences. (Kuo Chia K'o Hsueh Wei Yuan Hui, 2 Canton St., Taipei 107, Taiwan) V.1- 1973- Volume(issue)/page/year: 8,551,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	N:Dangerousfortheenvironment;
Risk Phrases	R51/53
Safety Phrases	S60
RIDADR	UN 3077
RTECS	WO9350000
HS Code	2935009017

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HS Code	2935009017
Summary	2935009017 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1.

Plant Cell 23(9) , 3412-27, (2011)

The dynamic instability of cortical microtubules (MTs) (i.e., their ability to rapidly alternate between phases of growth and shrinkage) plays an essential role in plant growth and development. In add...

Arabidopsis dynamin-related proteins, DRP2A and DRP2B, function coordinately in post-Golgi trafficking.

Biochem. Biophys. Res. Commun. 456(1) , 238-44, (2015)

Dynamin-related proteins (DRPs) are large GTPases involved in a wide range of cellular membrane remodeling processes. In Arabidopsis thaliana, two paralogous land plant-specific type DRPs, DRP2A and D...

Microtubules Are Essential for Guard-Cell Function in Vicia and Arabidopsis

Mol. Plant 5(3) , 601-10, (2012)

Radially arranged cortical microtubules are a prominent feature of guard cells. Guard cells expressing GFP-tubulin showed consistent changes in the appearance of microtubules when stomata opened or cl...

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
Source: NCGC
Target: N/A
External Id: OBG420

Total 296, Current Page 1 of 30

4-(dipropylamino)-3,5-dinitrobenzene-1-sulfonamide

Surflan

Caswell No. 623A

4-(dipropylamino)-3,5-dinitrobenzenesulfonamide

Ryzelan

MFCD00078725

3,5-dinitro-N4,N4-dipropylsulfanilamide

Dirimal

ORYZALIN

3,5-Dinitro-4-dipropylamino-benzenesulphonamide

Dinitrodipropylsulfanilamide

Dirimal Extra

3,5-dinitro-N',N'-dipropylsulfanilamide

EINECS 242-777-0

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.