2227-13-6

2227-13-6 structure

Name: 4-Chlorphenyl-2,4,5-trichlorphenylsulfid
Chemical Name: tetrasul
CAS Number: 2227-13-6
Molecular Formula: C₁₂H₆Cl₄S
Molecular Weight: 324.05
Catalog: analytical chemistry Standard Pesticides, veterinary drugs and fertilizers
Create Date: 2018-07-13 11:22:13
Modify Date: 2026-07-19 21:12:11
Tetrasul is an acaricide. Tetrasul inhibits Tetranychus urticae and aphids on hops. Tetrasul has also been used in research of erythematous (type one) rosacea[1].

Name	tetrasul
Synonyms	2,4,4’,5-tetrachlorodiphenylsulfide 1,2,4-Trichloro-5-[(4-chlorophenyl)thio]benzene p-chlorophenyl2,4,5-trichlorophenylsulfide p-chlorophenyl-2,4,5-trichlorophenylsulphide [Tetrasul] 1,2,4-Trichloro-5-[(4-chlorophenyl)sulfanyl]benzene 2,4,4',5-TETRACHLORODIPHENYLSULPHIDE v101 Tetrasul in Acetone 1,2,4-trichloro-5-((4-chlorophenyl)thio)-benzen 4-chlorophenyl2,4,5-trichlorophenylsulfide animertv-10 TETRASUL 1,2,4-trichloro-5-(4-chlorophenyl)sulfanyl-benzene (4-chloro-phenyl)-(2,4,5-trichloro-phenyl)-sulfide Animert V-10 animertv-101 Benzene, 1,2,4-trichloro-5-[(4-chlorophenyl)thio] 1,2,4-trichloro-5-[(4-chlorophenyl)thio]benzene tetradisul (canada) C17420000 Tetrasul sulfide,p-chlorophenyl2,4,5-trichlorophenyl Animert Philips-duphar V-101 ent27 2454TETRACHLORODIPHENYLSULPHIDE 4-Chlorophenyl 2,4,5-trichlorophenyl sulfide Animert V-10K Animert V-101 Tetrasul@1000 μg/mL in Methanol tetrasul (bsi,iso,esa) EINECS 218-761-4 MFCD00018649 Caswell No. 213 ATRATON PESTANAL (2-ETHYLAMINO-4-ISOPROP 4-chlorophenyl 2,4,5-trichlorophenyl sulphide diphenylsulphide Tetrasul 100 μg/ml Ethyl acetate Tetrasul @100 μg/mL in Methanol Tetrasul [BSI:ISO] animert tetradisul 2,4,5,4’-tetrachlorodiphenylsulfide 3,4,6,4’-tetrachlor-diphenylsulfid animertv-10k Tetrasul 1000 μg/mL in Acetone 1,2,4-trichloro-5-(4-chlorophenyl)sulfanylbenzene Valdecoxib Impurity 1 Triethylammonium Salt (4-Chlor-phenyl)-(2,4,5-trichlor-phenyl)-sulfid 2,4,4',5-TETRACHLORODIPHENYL SULFIDE 2,4,5-Trichlorophenyl 4-chlorophenyl sulfide philips-duphv-101

Description	Tetrasul is an acaricide. Tetrasul inhibits Tetranychus urticae and aphids on hops. Tetrasul has also been used in research of erythematous (type one) rosacea[1].
Related Catalog	Research Areas >> Infection
Target	Tetranychus urticae and aphids[1].
References	[1]. Cone W W. Two-Spotted Spider Mite and Hop Aphid Control on Cluster Hops with Acaricides. J Econ Entomol. 1968, 61(6): 1685-1689.

Density	1.6±0.1 g/cm3
Boiling Point	408.1±45.0 °C at 760 mmHg
Molecular Formula	C₁₂H₆Cl₄S
Molecular Weight	324.05
Flash Point	185.9±25.9 °C
Exact Mass	321.894440
PSA	25.30000
LogP	7.27
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.679

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WQ3850000

CHEMICAL NAME :: Sulfide, p-chlorophenyl 2,4,5-trichlorophenyl

CAS REGISTRY NUMBER :: 2227-13-6

BEILSTEIN REFERENCE NO. :: 1884271

LAST UPDATED :: 199612

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C12-H6-Cl4-S

MOLECULAR WEIGHT :: 324.04

WISWESSER LINE NOTATION :: GR DSR BG DG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3960 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BESAAT Bulletin of the Entomological Society of America. (Entomological Soc. of America, 4603 Calvert Rd., College Park, MD 20740) V.1- 1955- Volume(issue)/page/year: 15,129,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >6810 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5010 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,495,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >6810 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1350 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,55,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 8200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year: -,-,1971/1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 406000 mg/kg/116W-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - thyroid weight (goiter) Endocrine - changes in thyroid weight

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg/12W-C

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Endocrine - changes in thyroid weight

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,113,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2016 mg/kg/12W-C

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Endocrine - changes in thyroid weight

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,103,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2520 mg/kg/12W-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thyroid weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,103,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - pig

DOSE/DURATION :: 3444 mg/kg/12W-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thyroid weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,103,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5040 mg/kg/12W-C

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,103,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 14700 mg/kg/12W-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thyroid weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,103,1973 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 18 gm/kg

SEX/DURATION :: male 17 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 18 gm/kg

SEX/DURATION :: female 17 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 1,63,1973 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 56,107,1975

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H312-H412
Precautionary Statements	P273-P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R21
Safety Phrases	S36
RIDADR	NONH for all modes of transport
RTECS	WQ3850000
HS Code	2930909090

636-30-6

2227-13-6

Literature: Chemosphere, , vol. 38, # 15 p. 3529 - 3539

45889-73-4

106-54-7

2227-13-6

Literature: Chemosphere, , vol. 38, # 15 p. 3529 - 3539

18803-44-6

2227-13-6

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 80, p. 1057 - 1065

120-82-1

2227-13-6

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 80, p. 1057 - 1065

90309-42-5

2227-13-6

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 77, p. 103,112, 114

100-00-5

2227-13-6

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 77, p. 103,112, 114

3773-14-6

2227-13-6

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 77, p. 103,112, 114

95-94-3

18803-44-6

2227-13-6

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 80, p. 1057 - 1065

90309-24-3

2227-13-6

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 77, p. 103,112, 114

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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