24769-56-0

24769-56-0 structure

Name: tetranor-PGEM (tetranor-Prostaglandin E Metabolite)
Chemical Name: 9,15-dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid
CAS Number: 24769-56-0
Molecular Formula: C₁₆H₂₄O₇
Molecular Weight: 328.358
Catalog: Research Areas Cancer
Create Date: 2016-07-08 17:09:32
Modify Date: 2024-01-04 12:45:29
PGE-M is a metabolite of prostaglandin E2 (PEG2) as a biomarker of inflammation and cancer including advanced colorectal neoplasia, ovarian cancer, prostate cancer and so on. Urinary PGE-M is positively associated with obesity, smoking and lung metastases with breast cancer[1][2][3].

Name	9,15-dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid
Synonyms	8-[(1R,2R,5R)-2-(2-Carboxyethyl)-5-hydroxy-3-oxocyclopentyl]-6-oxooctanoic acid Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-η,3-dioxo-, (1R,2R,5R)- 11alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoicacid 8-[(1R,2R,5R)-2-(2-Carboxyethyl)-5-hydroxy-3-oxocyclopentyl]-8-oxooctanoic acid TETRANOR-PGEM tetranor-prostaglandin E metabolite Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-ε,3-dioxo-, (1R,2R,5R)- tetranor-PGEM Lipid Maps MS Standard

Description	PGE-M is a metabolite of prostaglandin E2 (PEG2) as a biomarker of inflammation and cancer including advanced colorectal neoplasia, ovarian cancer, prostate cancer and so on. Urinary PGE-M is positively associated with obesity, smoking and lung metastases with breast cancer[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology
References	[1]. Johnson JC, et al. Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin Gastroenterol Hepatol. 2006 Nov;4(11):1358-65. [2]. Wang D, DuBois RN. Urinary PGE-M: a promising cancer biomarker. Cancer Prev Res (Phila). 2013 Jun;6(6):507-10. [3]. Morris PG, et al. Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer. Cancer Prev Res (Phila). 2013 May;6(5):428-36.

HS Code	2918990090

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%