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87-87-6

87-87-6 structure
87-87-6 structure
  • Name: Tetrachlorohydroquinone
  • Chemical Name: tetrachlorohydroquinone
  • CAS Number: 87-87-6
  • Molecular Formula: C6H2Cl4O2
  • Molecular Weight: 247.89
  • Catalog: Chemical reagent Organic reagent Fatty ketone (including enol)
  • Create Date: 2018-08-11 14:25:53
  • Modify Date: 2024-01-02 02:56:13
  • Tetrachlorohydroquinone (TCHQ) is a metabolite of pentachlorophenol. Tetrachlorohydroquinone increases DNA lesions and induce oxidative stress in rodents[1].

Name tetrachlorohydroquinone
Synonyms Tetrachlorohydroquinone
EINECS 201-779-1
MFCD00041748
2,3,5,6-tetrachlorobenzene-1,4-diol
Description Tetrachlorohydroquinone (TCHQ) is a metabolite of pentachlorophenol. Tetrachlorohydroquinone increases DNA lesions and induce oxidative stress in rodents[1].
Related Catalog
References

[1]. Pietsch C, et al. Cytotoxic effects of pentachlorophenol (PCP) and its metabolite tetrachlorohydroquinone (TCHQ) on liver cells are modulated by antioxidants. Cell Biol Toxicol. 2014 Aug;30(4):233-52.  

Density 1.848 g/cm3
Boiling Point 286.2ºC
Melting Point 238-240 °C
Molecular Formula C6H2Cl4O2
Molecular Weight 247.89
Flash Point 126.9ºC
Exact Mass 245.88100
PSA 40.46000
LogP 3.71140
Index of Refraction 1.661

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MX7700000
CHEMICAL NAME :
Hydroquinone, tetrachloro-
CAS REGISTRY NUMBER :
87-87-6
BEILSTEIN REFERENCE NO. :
1876374
LAST UPDATED :
199710
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C6-H2-Cl4-O2
MOLECULAR WEIGHT :
247.88
WISWESSER LINE NOTATION :
QR BG CG EG FG DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3319 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
368 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - muscle weakness
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
50 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 145,71,1985
Hazard Codes Xn: Harmful;
Risk Phrases 22-41
Safety Phrases S26-S36/37/39-S39
RTECS MX7700000
HS Code 2908199090
HS Code 2908199090
Summary HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%