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Product Name: colchicoside
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477-29-2

477-29-2 structure

477-29-2 structure

Name: Colchicoside
Chemical Name: Colchicoside
CAS Number: 477-29-2
Molecular Formula: C₂₇H₃₃NO₁₁
Molecular Weight: 547.55
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-03-30 08:00:00
Modify Date: 2026-07-15 14:55:29
Colchicoside is a bioactive tropolone alkaloid with anti-leishmanial and anti-leishmanial?activities[1].

Name	Colchicoside
Synonyms	Acetamide, N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]htalen-7-yl] N-[(7S,12a)-3-(beta-D-Glucopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]htale N-[3-(Hexopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[A]htalen-7-yl]acetamide Aids-012001 N-[(7S,12a)-3-(beta-D-Glucopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]htalen-7-yl]acetamide (Colchicoside) N-[(7S)-3-(β-D-Glucopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide Colchicine impurity D Colchicoside, 10 mM in DMSO COLCHICOSIDE //BP Colchicine impurity D (Colchicoside) (S)-7-Acetylamino-6,7-dihydro-3-(β-D-glucopyranosyloxy)-1,2,10-trimethoxybenzo[a]htalen-9(5H)-one (S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-triMethoxy-9-oxobenzo[a]htalen-7-yl]acetaMide Aids012001 colchicoside N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro- 1,2,10-triMethoxy-9-oxobenzo[a]htalen-7-yl]acetaMide N-[(7S,12a)-3-(beta-D-Glucopyrano Thiocolchicoside Impurity D Nsc32992 N-((S)-1,2,10-trimethoxy-9-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5,6,7,9-tetrahydrobenzo[a]htalen-7-yl)acetamide ColchicosideQ: What is Colchicoside Q: What is the CAS Number of Colchicoside Q: What is the storage condition of Colchicoside Q: What e the applications of Colchicoside N-[(7S,12a)-3-(β-D-glucopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]htalen-7-yl]acetamide (colchicoside) 3-Demethylcolchicine glucoside COLCHICOSIDE IMPURITY Colchicine Impurity 4（Colchicine Impurity D） Nsc624672

Description	Colchicoside is a bioactive tropolone alkaloid with anti-leishmanial and anti-leishmanial?activities[1].
Related Catalog	Research Areas >> Infection
References	[1]. Mohammad Azadbakht, et al. Tropolone alkaloids from Colchicum kurdicum (Bornm.) Stef. (Colchicaceae) as the potent novel antileishmanial compounds; purification, structure elucidation, antileishmanial activities and molecular docking studies. Exp Parasitol. 2020 Jun;213:107902.

Density	1.4±0.1 g/cm3
Boiling Point	929.0±65.0 °C at 760 mmHg
Melting Point	194-197ºC
Molecular Formula	C₂₇H₃₃NO₁₁
Molecular Weight	547.55
Flash Point	515.6±34.3 °C
Exact Mass	547.205383
PSA	173.24000
LogP	-1.76
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.636

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0982000

CHEMICAL NAME :: Colchicoside

CAS REGISTRY NUMBER :: 477-29-2

BEILSTEIN REFERENCE NO. :: 0072204

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C27-H33-N-O11

MOLECULAR WEIGHT :: 547.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 75 ug/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 109,386,1957

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 75 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 15,533,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 84 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,453,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 109,386,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,453,1953

Hazard Codes	T+

Precursor 0
DownStream 2
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