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13957-31-8

13957-31-8 structure
13957-31-8 structure
  • Name: 4-thiouridine
  • Chemical Name: 4-thiouridine
  • CAS Number: 13957-31-8
  • Molecular Formula: C9H12N2O5S
  • Molecular Weight: 260.267
  • Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
  • Create Date: 2018-09-02 18:04:28
  • Modify Date: 2024-01-09 18:05:41
  • 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1].

Name 4-thiouridine
Synonyms EINECS 237-735-3
2(1H)-Pyrimidinone, 3,4-dihydro-1-β-D-ribofuranosyl-4-thioxo-
4-Thio-uridin
4-Thio-D-uridine
MFCD00006538
4-thio-uridine
1-(β-D-Ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Uridine,4-thio
thiouridine
4-SH-Ur
THIOURIDINE,4
4-thiouridine
Description 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1].
Related Catalog
In Vitro 4-thiouridine (0-10 μM) labels and purifies nascent rRNA without significantly affecting rRNA synthesis[1]. 4-thiouridine (≥50 μM) strongly inhibits production and processing of rRNA[1].
References

[1]. Burger K, et al. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 2013 Oct;10(10):1623-30.

Density 1.7±0.1 g/cm3
Melting Point 139-140℃ (ethanol )
Molecular Formula C9H12N2O5S
Molecular Weight 260.267
Exact Mass 260.046692
PSA 139.80000
LogP -0.21
Index of Refraction 1.733
Storage condition −20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes C
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%