4372-67-2

4372-67-2 structure

Name: 8-azidoadenosine
Chemical Name: 8-Azido Adenosine
CAS Number: 4372-67-2
Molecular Formula: C₁₀H₁₂N₈O₄
Molecular Weight: 308.25
Catalog: Inorganic chemical industry Inorganic salt Hydride, nitride, azide Azide
Create Date: 2018-04-22 08:00:00
Modify Date: 2026-07-16 18:29:57
8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Name	8-Azido Adenosine
Synonyms	8-N3-ADO (2R,3R,4S,5R)-2-(6-amino-8-azido-purin-9-yl)-5-methylol-tetrahydrofuran-3,4-diol 8-AZIDO-D-ADENOSINE Adenosine Impurity 48 Adenosine, 8-azido (2R,3R,4S,5R)-2-(6-amino-8-azidopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 8-AZIDOADENOSINE ISO 9001：2015 REACH (2R,3R,4S,5R)-2-(6-amino-8-azido-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 8-AZIDOADENOSINE (2R,3R,4S,5R)-2-(6-azanyl-8-azido-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 8-azido-adenosin

Description	8-Azidoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Melting Point	>200ºC (dec.)
Molecular Formula	C₁₀H₁₂N₈O₄
Molecular Weight	308.25
Exact Mass	308.09800
PSA	189.29000
Storage condition	Amber Vial, Refrigerator, Under Inert Atmosphere

58-61-7

~75%

4372-67-2

Literature: Sayed Ahmed Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 6 p. 595 - 597

2946-39-6

~57%

4372-67-2

Literature: Frieden, Miriam; Avino, Anna; Eritja, Ramon Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 2 p. 193 - 202