55750-63-5
55750-63-5 structure
- Name: N-Succinimidyl 6-maleimidohexanoate
- Chemical Name: N-Succinimidyl 6-maleimidohexanoate
- CAS Number: 55750-63-5
- Molecular Formula: C14H16N2O6
- Molecular Weight: 308.287
- Catalog: Chemical reagent Organic reagent Ester Other ester compounds
- Create Date: 2018-12-24 15:28:45
- Modify Date: 2026-07-03 10:08:08
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6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.
| Name | N-Succinimidyl 6-maleimidohexanoate |
|---|---|
| Synonyms |
6-maleimidohexanoic acid N-hydroxylsuccinimide ester, N-succinimidyl-6-maleimidylhexanoate
N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate N-SUCCINIMIDYL 6-MALEIMIDOCAPROATE N-silon-Maleimidocaproyloxy) Succinimide extrapure 1H-Pyrrole-1-hexanoicacid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl 6-MaleiMidohexanoic acid N-hydroxysucciniMide este N-(6-Maleimidocaproyloxy)succinimideN-Succinimidyl-6-maleimidohexanoate 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate 6-maleimidohexanoic acid n-succinimidyl ester EMCS Crosslinker (2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate 6-Maleimidocaproic acid N-succinimidyl ester, N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS 6-Maleimidohexanoic acid-NHS ester 6-Maleimidohexanoic acidN-hydroxysuccinimide ester (HPLC) 6-Maleimidohexanoic acid N-hydroxysuccinimide ester N-Succinimidyl 6-maleimidohexanoate(EMCS) maleimide-(CH2)5-NHS 6-Maleimidohexanoic acid N-hydroxy succinimidyl ester Succinimide 6-(maleimide) caproate EMCS ISILON-MALEIMIDOCAPROIC ACID N-*HYDROX YSUCCINIMID Succinimide ester of 6-(maleimide) caproate 6-MaleiMidocaproic acid NHS Mal-htanoic NHS ester 6-Maleimidohexanoic Acid N-hydroxy Succinimidyl Este N-Succinimidyl6-Maleimidohexanoate[Cross-linkineagent]> MFCD00043043 N-Succinimidyl 6-Maleimidohexanoate [Cross-linking ] MCOSU (2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate NHS-(CH2)5-Mal (EMCS) 6-Maleimidocaproic acid N-hydroxysuccinimide ester N-SILON-MALEIMIDOCAPROYLOXY)SUCCI EMCS N-Succinimidyl 6-maleimidohexanoate N-(6-MALEIMIDOCAPROYLOXY)SUCCINIMIDE N-SILON-MALEIMIDOCAPROYLOXY]SUCCINIMIDE ESTER N-(6-Maleimidocaproyloxy)succinimide (EMCS) N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) N-(6-Maleimidocaproyloxy)succinimine 6-maleimidohexanoic acid N-hydroxylsuccinimide ester 1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione N-SUCCINIMIDYL-6-MALEMIDOCAPROATE N-(E-MALEIMIDOCAPROYLOXY)SUCCINIMIDE 6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER N-Succinimidyl 6-maleimidohexanoate 6-Maleimidohexanoic acid N-hydroxysuccinimide ester Mcosu N-SILON-MALEIMIDOCAPROYLOXY)SUCCINIMIDE 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester Maleimide-(CH2)5-COONHS N-succinimidyl 6-maleimide hexanoate (SMPH) 1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione SILON-MALEIMIDOCAPROIC ACID N-HYDROXYSUCCINIMIDE ESTER N-succinimidyl-6-maleimidocaproate |
| Description | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 480.6±47.0 °C at 760 mmHg |
| Melting Point | 70-73 °C(lit.) |
| Molecular Formula | C14H16N2O6 |
| Molecular Weight | 308.287 |
| Flash Point | 244.5±29.3 °C |
| Exact Mass | 308.100830 |
| PSA | 101.06000 |
| LogP | -0.81 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.577 |
| Storage condition | −20°C |
| Water Solubility | chloroform: 100mg/mL |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335-H351 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful;Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
|
~91%
55750-63-5 |
| Literature: MacBeath; Hilvert Journal of the American Chemical Society, 1994 , vol. 116, # 14 p. 6101 - 6106 |
|
~82%
55750-63-5 |
| Literature: Ikeda, Masato; Ochi, Rika; Kurita, Yu-Shi; Pochan, Darrin J.; Hamachi, Itaru Chemistry - A European Journal, 2012 , vol. 18, # 41 p. 13091 - 13096 |
|
~38%
55750-63-5 |
| Literature: Augustin, Manfred; Mueller, Wolfgang Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798 |
|
~%
55750-63-5 |
| Literature: Organic and Biomolecular Chemistry, , vol. 7, # 17 p. 3400 - 3406 |
|
~%
55750-63-5 |
| Literature: Journal of Organic Chemistry, , vol. 76, # 21 p. 9169 - 9174 |
| Precursor 6 | |
|---|---|
| DownStream 1 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |