Name | N-Succinimidyl 6-maleimidohexanoate |
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Synonyms |
1-{6-[(2,5-Dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione
MFCD00043043 1-{6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl}-1H-pyrrole-2,5-dione 1H-pyrrole-2,5-dione, 1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]- (2,5-dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate N-succinimidyl-6-maleimidocaproate 6-Maleimidohexanoic acid N-hydroxysuccinimide ester MCOSU EMCS |
Description | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. |
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Related Catalog |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 480.6±47.0 °C at 760 mmHg |
Melting Point | 70-73 °C(lit.) |
Molecular Formula | C14H16N2O6 |
Molecular Weight | 308.287 |
Flash Point | 244.5±29.3 °C |
Exact Mass | 308.100830 |
PSA | 101.06000 |
LogP | -0.81 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.577 |
Storage condition | −20°C |
Water Solubility | chloroform: 100mg/mL |
Symbol |
GHS07, GHS08 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335-H351 |
Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn: Harmful;Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36/37-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2925190090 |
~91% 55750-63-5 |
Literature: MacBeath; Hilvert Journal of the American Chemical Society, 1994 , vol. 116, # 14 p. 6101 - 6106 |
~82% 55750-63-5 |
Literature: Ikeda, Masato; Ochi, Rika; Kurita, Yu-Shi; Pochan, Darrin J.; Hamachi, Itaru Chemistry - A European Journal, 2012 , vol. 18, # 41 p. 13091 - 13096 |
~38% 55750-63-5 |
Literature: Augustin, Manfred; Mueller, Wolfgang Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798 |
~% 55750-63-5 |
Literature: Organic and Biomolecular Chemistry, , vol. 7, # 17 p. 3400 - 3406 |
~% 55750-63-5 |
Literature: Journal of Organic Chemistry, , vol. 76, # 21 p. 9169 - 9174 |
Precursor 6 | |
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DownStream 1 | |
HS Code | 2925190090 |
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Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |