- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 6-Maleimidocapronic acid
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 6-Maleimidocapronic acid
- Price: ￥138.0/5g ￥498.0/25g ￥248.0/10g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: 6-Maleimidocapronic acid
- Price: ￥Inquiry/10g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- DC Chemicals Limited
- China
- Product Name: 6-Maleimidocaproic acid
- Price: $200.0/100mg $400.0/250mg $800.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 6-Maleimidocaproic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
55750-53-3
55750-53-3 structure
- Name: 6-Maleimidocapronic acid
- Chemical Name: 6-Maleimidocaproic Acid
- CAS Number: 55750-53-3
- Molecular Formula: C10H13NO4
- Molecular Weight: 211.214
- Catalog: Organic raw materials Carboxylic compounds and derivatives Acyclic carboxylic acid
- Create Date: 2018-06-13 20:49:35
- Modify Date: 2024-01-03 21:27:12
-
6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 6-Maleimidocaproic Acid |
|---|---|
| Synonyms |
6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid
MFCD00043140 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo- 6-(2,5-dioxopyrrol-1-yl)hexanoic acid |
| Description | 6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 407.3±28.0 °C at 760 mmHg |
| Melting Point | 86-91ºC |
| Molecular Formula | C10H13NO4 |
| Molecular Weight | 211.214 |
| Flash Point | 200.1±24.0 °C |
| Exact Mass | 211.084457 |
| PSA | 74.68000 |
| LogP | 0.71 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.537 |
| Storage condition | 2-8°C |
| Symbol |
GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H315-H318-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
|
~71%
55750-53-3 |
| Literature: Dalton Transactions, , # 24 p. 3886 - 3897 |
|
~74%
55750-53-3 |
| Literature: Journal of Medicinal Chemistry, , vol. 56, # 24 p. 9955 - 9968 |
|
~30%
55750-53-3 |
| Literature: EP665020 A3, ; |
|
~%
55750-53-3 |
| Literature: US8241655 B2, ; |
|
~%
55750-53-3 |
| Literature: Dalton Transactions, , # 24 p. 3886 - 3897 |
| Precursor 4 | |
|---|---|
| DownStream 4 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |