Henan Tianfu Chemical Co., Ltd.
China
Product Name: formamide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Formamide
Price: ￥Inquiry/25kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

75-12-7

75-12-7 structure

Name: Formamide
Chemical Name: formamide
CAS Number: 75-12-7
Molecular Formula: CH₃NO
Molecular Weight: 45.041
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Fluoropyrimidine
Create Date: 2018-08-08 17:14:57
Modify Date: 2026-06-30 11:43:34
Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.

Name	formamide
Synonyms	potassium deuteroformate Formylamide FORMAMIDE,DEIONIZED,ULTRAPURE AMIDE C1 Formamide,for spectroscopy Formimidic acid Formamide,Amide C1, Formic amide FORMIC AMIDE Formide Formamide . p.a. >= /T) FORMAMIDE FORMAMIDE,ULTRAPURE FORMIC ACID AMIDE Formamide , >= formimidicacid FORMAMIDE extrapure Formamide, Spectrophotometric ade CBAMALDEHYDE Formamide, Spectrophotometric, min methanoicacid,amide Formamide, extra Formamide for analysis Formamide4x Hydroxyformaldimin HCONH2 Amide C1, Formic amide amidkyselinymravenci Formamid Formamine ForMaMide, Electrophoresis ade Kalium-d-formiat Formamide, for poloaphic and nonaqueous titration, for analysis Potassium formate-d Formamide ReagentPlus(R), >= Formic amide FORMAMIDE BIO-REFINED Amid kyseliny mravenci methanimidic acid Formamide in Dimethyl Sulfoxide, 467 Standd Formamide Vetec(TM) ade formamidic acid Formamide, DNase, RNase and Protease Free FORMAMIDE,BIOSOLV FORMAMIDE, DEIONIZED Formamide, ade Formimidsaeure Ameisensαureamid Formamide solution Formamide extra formimidic acid Formamide,for analysis,for poloaphic andnonaqueous titration METHANAMIDE Formamide, for spectroscopy Residual Solvent Class 2 - Formamide Formamide, For analysis Formamide,for moleculbiology,DNAse, RNAse and Protease free FORMAMIDE,OMNISOLV F-amide Formamide MFCD00007941 AMINOFORMALDEHYDE formic-d acid,potassium salt EINECS 200-842-0

Description	Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.
Related Catalog	Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others

Density	1.0±0.1 g/cm3
Boiling Point	210.5±9.0 °C at 760 mmHg
Melting Point	2-3 °C(lit.)
Molecular Formula	CH₃NO
Molecular Weight	45.041
Flash Point	81.1±18.7 °C
Exact Mass	45.021465
PSA	43.09000
LogP	-1.51
Vapour density	1.55 (vs air)
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.370
Water Solubility	miscible

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LQ0525000

CHEMICAL NAME :: Formamide

CAS REGISTRY NUMBER :: 75-12-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 42

MOLECULAR FORMULA :: C-H3-N-O

MOLECULAR WEIGHT :: 45.05

WISWESSER LINE NOTATION :: ZVH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5577 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - ataxia Kidney, Ureter, Bladder - incontinence

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >13500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 910 mg/kg/26W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Liver - liver function tests impaired Kidney, Ureter, Bladder - proteinuria

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 ppm/6H/2W-I

TOXIC EFFECTS :: Blood - changes in leukocyte (WBC) count Blood - changes in platelet count Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2 gm/kg

SEX/DURATION :: female 7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 7980 mg/kg

SEX/DURATION :: female 7-12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 1200 mg/kg

SEX/DURATION :: female 10-11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 910 mg/kg

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Non-mammalian species Cells - not otherwise specified

REFERENCE :: CAANAT Comptes Rendus de l'Association des Anatomistes. (Nancy, France) V.1-56, 1899-1972. For publisher information, see ANOBAU. Volume(issue)/page/year: 56,712,1972 *** REVIEWS *** ACGIH TLV-TWA 18 mg/m3 (10 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 10 ppm (15 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 10 ppm (18 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 20 ppm (30 mg/m3) JAN 1993 OEL-FINLAND:TWA 20 ppm (37 mg/m3);STEL 30 ppm (55 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 20 ppm (30 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 20 ppm (30 mg/m3) JAN 1993 OEL-RUSSIA:STEL 3 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 20 ppm (37 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 20 ppm (30 mg/m3);STEL 30 ppm (45 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO FORMAMIDE-air:10H TWA 10 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84454 No. of Facilities: 227 (estimated) No. of Industries: 6 No. of Occupations: 14 No. of Employees: 3195 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84454 No. of Facilities: 42 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 2724 (estimated) No. of Female Employees: 556 (estimated)

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H351-H360D-H373
Precautionary Statements	P201-P281-P308 + P313
Target Organs	Blood
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic
Risk Phrases	R61
Safety Phrases	S53-S45-S36/37/39-S26-S23
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	LQ0525000
HS Code	2924199090

77287-34-4

75-12-7

Literature: Maier, Guenther; Endres, Joerg European Journal of Organic Chemistry, 2000 , # 6 p. 1061 - 1063

Precursor 1
77287-34-4
DownStream 0

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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