- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one
- Price: Check
- Purity: 95.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one
- Price: ￥4418.0/5mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Aristolactam BIII
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: ARISTOLACTAM BIII
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
53948-10-0
53948-10-0 structure
- Name: 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one
- Chemical Name: 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one
- CAS Number: 53948-10-0
- Molecular Formula: C18H15NO4
- Molecular Weight: 309.316
- Catalog: Natural product Alkaloid
- Create Date: 2018-08-08 14:08:56
- Modify Date: 2025-08-21 01:43:16
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Aristolactam BIII is a potent DYRK1A inhibitor and inhibits the kinase activity of DYRK1A in vitro (IC50= 9.67 nM. Aristolactam BIII rescues the proliferative defects of DYRK1A transgenic (TG) mouse-derived fibroblasts and neurological and phenotypic defects of DS-like Drosophila models[1].
| Name | 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one |
|---|---|
| Synonyms |
Dibenz[cd,f]indol-4(5H)-one, 1,2,9-trimethoxy-
3,4,6-trimethoxyaristolactame aristolactam A II Aristololactam B III 1,2,9-Trimethoxydibenzo[cd,f]indol-4(5H)-one aristololactam A-II Dibenz(cd,f)indol-4(5H)-one,2-hydroxy-1-methoxy aristolactam BIII |
| Description | Aristolactam BIII is a potent DYRK1A inhibitor and inhibits the kinase activity of DYRK1A in vitro (IC50= 9.67 nM. Aristolactam BIII rescues the proliferative defects of DYRK1A transgenic (TG) mouse-derived fibroblasts and neurological and phenotypic defects of DS-like Drosophila models[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 462.8±45.0 °C at 760 mmHg |
| Molecular Formula | C18H15NO4 |
| Molecular Weight | 309.316 |
| Flash Point | 233.7±28.7 °C |
| Exact Mass | 309.100098 |
| PSA | 60.28000 |
| LogP | 3.23 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.681 |
| HS Code | 2933990090 |
|---|
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |