41743-74-2
41743-74-2 structure
- Name: toralactone
- Chemical Name: toralactone
- CAS Number: 41743-74-2
- Molecular Formula: C15H12O5
- Molecular Weight: 272.25300
- Catalog: Signaling Pathways NF-κB Keap1-Nrf2
- Create Date: 2017-08-22 17:48:21
- Modify Date: 2024-01-15 20:30:38
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Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism[1].
| Name | toralactone |
|---|---|
| Synonyms |
Toralactone
9,10-dihydroxy-7-methoxy-3-methylbenzo[g]isochromen-1-one 9,10-Dihydroxy-7-methoxy-3-methyl-1H-naphtho(2,3-c)pyran-1-one torolactone |
| Description | Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity[2]. |
| References |
| Density | 1.432g/cm3 |
|---|---|
| Boiling Point | 480.2ºC at 760mmHg |
| Molecular Formula | C15H12O5 |
| Molecular Weight | 272.25300 |
| Flash Point | 184.8ºC |
| Exact Mass | 272.06800 |
| PSA | 79.90000 |
| LogP | 2.67440 |
| Index of Refraction | 1.691 |
| Storage condition | 2-8℃ |
| HS Code | 2932999099 |
|---|
|
~85%
41743-74-2 |
| Literature: Zhang, Zhaojun; Yu, Biao Journal of Organic Chemistry, 2003 , vol. 68, # 16 p. 6309 - 6313 |
|
~%
41743-74-2 |
| Literature: Kitanaka, Susumu; Takido, Michio Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 10 p. 3980 - 3984 |
|
~%
41743-74-2 |
| Literature: Zhang, Zhaojun; Yu, Biao Journal of Organic Chemistry, 2003 , vol. 68, # 16 p. 6309 - 6313 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |