55104-39-7

55104-39-7 structure

Name: DL-071-IT
Chemical Name: 7-[3-(tert-butylamino)-2-hydroxypropoxy]-3H-2-benzofuran-1-one,hydrochloride
CAS Number: 55104-39-7
Molecular Formula: C₁₅H₂₂ClNO₄
Molecular Weight: 315.79
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2017-04-24 19:41:20
Modify Date: 2024-03-03 18:35:16
DL 071IT is a potent non-selective beta-adrenergic receptor blocker. DL 071IT exhibits intrinsic sympathomimetic activity and weak membrane stabilizing activity. DL 071IT reduces exercise heart rate and systolic blood pressure, and even significantly lowers resting heart rate[1].

Name	7-[3-(tert-butylamino)-2-hydroxypropoxy]-3H-2-benzofuran-1-one,hydrochloride
Synonyms	1(3H)-Isobenzofuranone,7-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-,hydrochloride DL 071 IT DL-071-IT

Description	DL 071IT is a potent non-selective beta-adrenergic receptor blocker. DL 071IT exhibits intrinsic sympathomimetic activity and weak membrane stabilizing activity. DL 071IT reduces exercise heart rate and systolic blood pressure, and even significantly lowers resting heart rate[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	β adrenergic receptor
References	[1]. Radice M, et al. Pharmacodynamic studies in man of the beta-adrenoceptor antagonist DL 071 IT. Eur J Clin Pharmacol. 1979 Sep;16(2):87-90.