Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PTP1B-IN-3
Price: Check
Purity: 99.91%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Phosphonic acid, [(3-bromo-7-cyano-2-naphthalenyl)difluoromethyl]- (9CI)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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809272-64-8

809272-64-8 structure

809272-64-8 structure

Name: PTP1B-IN-3
Chemical Name: [(3-bromo-7-cyano-2-naphthyl)-(difluoro)methyl]phosphonic acid
CAS Number: 809272-64-8
Molecular Formula: C₁₂H₇BrF₂NO₃P
Molecular Weight: 362.06300
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2016-03-13 05:36:21
Modify Date: 2025-08-21 21:37:37
PTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively.

Name	[(3-bromo-7-cyano-2-naphthyl)-(difluoro)methyl]phosphonic acid
Synonyms	P-[(3-Bromo-7-cyano-2-naphthalenyl)difluoromethyl]phosphonic Acid PTP1B-IN-3

Description	PTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Metabolic Disease
Target	IC50: 120 nM (PTP1B), 120 nM (TCPTP) [1].
References	[1]. Patel D, .Discovery of orally active, potent, and selective benzotriazole-based PTP1B inhibitors. ChemMedChem. 2011 Jun 6; 6(6):1011-6.

Molecular Formula	C₁₂H₇BrF₂NO₃P
Molecular Weight	362.06300
Exact Mass	360.93100
PSA	91.13000
LogP	3.70098

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