4046-02-0
4046-02-0 structure
- Name: Ethyl ferulate
- Chemical Name: Ethyl 4'-hydroxy-3'-methoxycinnamate
- CAS Number: 4046-02-0
- Molecular Formula: C12H14O4
- Molecular Weight: 222.24
- Catalog: Chemical reagent Organic reagent Ester Ethyl ester compound
- Create Date: 2018-04-07 08:00:00
- Modify Date: 2026-07-02 20:54:58
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Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2].
| Name | Ethyl 4'-hydroxy-3'-methoxycinnamate |
|---|---|
| Synonyms |
(E)-ethyl 3-(4-hydroxy-3-Methoxyphenyl)acrylate
4-HYDROXY-3-METHOXYCINNAMIC ACID ETHYL ESTER ETHYL 4-HYDROXY-3-METHOXYCINNAMATE (FERULIC ACID ETHYL ESTER) Ethyl 4-hydroxy-3-methoxycinnamate,Ethyl ferulate MFCD00009190 ETHYL TRANS-3-(4'-HYDROXY-3'-METHOXYPHENYL)ACRYLATE FERULIC ACID ETHYL ESTER 4-Hydroxy-3-methoxycinnamic Acid Ethyl Ester ETHYL FERULATE Ethyl 4-Hydroxy-3-MethoxycinnaMate 3-(3-Methoxy-4-hydroxyphenyl)propenoic acid ethyl ester 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester EINECS 223-745-5 methoxycinnamate Ethyl ferulate~Ferulic acid ethyl ester~4-Hydroxy-3-methoxycinnamic acid ethyl ester ETHYL 4-HYDROXY-3-METHOXYCINNAMATE hyl 4'-hydroxy-3'-MethoxycinnaMate RECHEM AL BI 0735 Ferulic Acid Impurity 31 (Mixture of E/Z-isomers) ethyl4-hydro (E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid ethyl ester BUTTPK 121 Ethyl ferulate - Natural ade Ethyl 4'-hydroxy-3'-methoxycinnamate|||Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate|||Ferulic acid ethyl ester Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate, Ethyl ferulate, Ethyl 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate Ethyl Ferulate Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate 4-Hydroxy-3-methoxycinnamic Acid Ethyl Ester Ethyl Ferulate Ferulic Acid Ethyl Ester FeruL Ferulic acid ethyl ester Ferulic acid ethyl eser (E)-3-(4-HYDROXY-3-METHOXY-PHENYL)-ACRYLIC ACID ETHYL ESTER Natural Ethyl Ferulate ethyl Ferulic acid 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid ethyl ester Ethyl4-Hydroxy-3-methoxycinnamate> cis-3-(4-Hydroxy-3-Methoxyphenyl)-2-propensaeure-ethylester ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate thyl 4'-hydroxy-3'-methoxycinnamate erulic acid ethylester FERULIC ACID ETHYLESTER(RG) Ethyl 4-hydroxy-3-methoxyciamate |
| Description | Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 382.3±0.0 °C at 760 mmHg |
| Melting Point | 63-65 °C(lit.) |
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 |
| Flash Point | 132.5±17.2 °C |
| Exact Mass | 222.089203 |
| PSA | 55.76000 |
| LogP | 1.94 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.566 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2918990090 |
|
~93%
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| Literature: Molecules, , vol. 14, # 6 p. 2118 - 2126 |
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~96%
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| Literature: Tetrahedron, , vol. 59, # 7 p. 1049 - 1054 |
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~82%
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| Literature: Organic Letters, , vol. 14, # 15 p. 3902 - 3905 |
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~92%
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| Literature: Journal of the American Chemical Society, , vol. 134, # 46 p. 18889 - 18891 |
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~%
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| Literature: Tetrahedron, , vol. 57, # 2 p. 365 - 370 |
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~%
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| Literature: Liebigs Annalen der Chemie, , # 12 p. 2135 - 2140 |
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| Literature: Chemische Berichte, , vol. 85, p. 1181,1188 |
| Precursor 8 | |
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| DownStream 4 | |
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |