- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Ac-Asp-Glu-OH
- Price: $Inquiry/1kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: Spaglumic Acid
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
3106-85-2
3106-85-2 structure
- Name: Spaglumic Acid
- Chemical Name: n-acetyl-asp-glu
- CAS Number: 3106-85-2
- Molecular Formula: C11H16N2O8
- Molecular Weight: 304.253
- Catalog: Biochemical Peptide
- Create Date: 2018-02-14 08:00:00
- Modify Date: 2024-01-03 00:12:34
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Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain.
| Name | n-acetyl-asp-glu |
|---|---|
| Synonyms |
N-Acetyl-L-aspartyl-L-glutamic acid
N-acetyl-1-aspartylglutamic acid NAAGA AC-ASP-GLU SPAGLUMIC ACID N-(N-Acetyl-L-a-aspartyl)-L-glutamic Acid N-acetyl-L-aspartyl-L-glutamate N-Acetyl-L-α-aspartyl-L-glutamic acid isospaglumic acid L-Glutamic acid, N-acetyl-L-α-aspartyl- AC-ASP-GLU H2O AC-ASP-GLU-OH MFCD00076652 Tacrine hydrochloride N-acetyl-aspartatylglutamate N-(N-Acetyl-L-α-aspartyl)-L-glutamic acid glutamic acid, N-acetylaspartyl- ACETYL-D-E Naaxia NAAG N-Acetylaspartylglutamic acid NAAG Spaglumic acid |
| Description | Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | Isospaglumic acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. NAAG is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of NAAG and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 769.5±60.0 °C at 760 mmHg |
| Molecular Formula | C11H16N2O8 |
| Molecular Weight | 304.253 |
| Flash Point | 419.1±32.9 °C |
| Exact Mass | 304.090668 |
| PSA | 170.10000 |
| LogP | -1.96 |
| Vapour Pressure | 0.0±5.7 mmHg at 25°C |
| Index of Refraction | 1.540 |
| Storage condition | −20°C |
| Water Solubility | H2O: 50 mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924199090 |
| Precursor 1 | |
|---|---|
| DownStream 2 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |