Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: (+)-Dehydroabiethylamine
Price: ￥488.0/5g
Purity: 95.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Dehydroabietylamine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dehydroabietylamine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1446-61-3

1446-61-3 structure

1446-61-3 structure

Name: (+)-Dehydroabiethylamine
Chemical Name: dehydroabietylamine
CAS Number: 1446-61-3
Molecular Formula: C₂₀H₃₁N
Molecular Weight: 285.467
Create Date: 2018-07-02 13:20:36
Modify Date: 2024-01-02 09:45:28
Leelamine is a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine also inhibits pyruvate dehydrogenase kinases (PDKs). Leelamine exhibits anti-tumor activity[1].

Name	dehydroabietylamine
Synonyms	Leelamine hydrochloride,(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanaminehydrochloride EINECS 215-899-7 MFCD00213430 (+)-DehydroabietylaMine [Optical Resolving Agent] Dehydroabiethylamine

Description	Leelamine is a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine also inhibits pyruvate dehydrogenase kinases (PDKs). Leelamine exhibits anti-tumor activity[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> PDHK Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	CB1 CB2
References	[1]. Merarchi M, et, al. A Brief Overview of the Antitumoral Actions of Leelamine. Biomedicines. 2019 Jul 19;7(3):53.

Density	1.0±0.1 g/cm3
Boiling Point	382.9±11.0 °C at 760 mmHg
Melting Point	44.50℃
Molecular Formula	C₂₀H₃₁N
Molecular Weight	285.467
Flash Point	156.7±9.1 °C
Exact Mass	285.245636
PSA	26.02000
LogP	6.40
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.528
Storage condition	Desiccate at +4°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP8701000

CHEMICAL NAME :: Podocarpa-8,11,13-trien-15-amine, 13-isopropyl-

CAS REGISTRY NUMBER :: 1446-61-3

BEILSTEIN REFERENCE NO. :: 3084620

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H31-N

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C: Corrosive;Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TP8701000
HS Code	3806900090

31148-95-5 structure

31148-95-5

~%

1446-61-3 structure

1446-61-3

Literature: Svensk Kemisk Tidskrift, , vol. 66, p. 316,321

1740-19-8 structure

1740-19-8

~%

1446-61-3 structure

1446-61-3

Literature: Zhurnal Organicheskoi Khimii, , vol. 9, p. 756 - 758,778 - 780

141666-88-8 structure

141666-88-8

~%

1446-61-3 structure

1446-61-3

Literature: Tetrahedron, , vol. 53, # 42 p. 14355 - 14368

Precursor 2
31148-95-5 1740-19-8
DownStream 1
115269-93-7

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%