Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dehydroabietylamine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

1446-61-3

1446-61-3 structure

Name: (+)-Dehydroabiethylamine
Chemical Name: dehydroabietylamine
CAS Number: 1446-61-3
Molecular Formula: C₂₀H₃₁N
Molecular Weight: 285.467
Create Date: 2018-07-02 13:20:36
Modify Date: 2026-07-01 15:47:27
Leelamine is a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine also inhibits pyruvate dehydrogenase kinases (PDKs). Leelamine exhibits anti-tumor activity[1].

Name	dehydroabietylamine
Synonyms	(1R,4aS,10-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-isopropyl-1-phenanthrenemethanamine [1theta-(1alpha,4abeta,10aalpha)]-hylethyl) ((1R,4aS,10) LYLAMINE HYDROCHLORIDE (1R,4aS,10-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine Dehydroabiethylamine 1,4A-DIMETHYL-7-ISOPROPYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENEMETHYLAMINE 13-isopropylpodocpa-8,11,13-trien-15-amine (+)DehyroabietylaMine Pyruvate dehydrogenase kinase,PDH kinase,Dehydroabiethylamine,Inhibitor,PDHK,Cannabinoid Rector,inhibit 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine (+)-Dehydroabietylamine [Optical Resolving Agent] (1R,4AS,10-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-,4A-DIMETHYL-7-(1-METHYLETHYL)-1-PHENANTHRENEMETHANAMINE HYDROCHLORIDE (1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)-1α-phenanthrenemethanamine (1R,4aS,10-,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-phenanthrenemethanamine 7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl) 1-phenanthrenemethanamine,1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-met Dehydrobietylamine Leelamine HCl Leelamine hydrochloride MFCD00213430 (1R)-(1,2,3,4,4a,9,10,10aα-Octahydro-7-isopropyl-1,4aβ-dimethylphenanthrene)-1α-methanamine (+)-DehydroabietylaMine [Optical Resolving Agent] Dehydroabietylamine1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1- phenanthrenemethylamine (1r-(1alpha,4abeta,10aalpha))-hylethyl) AMINE D Dehydroabiethylamine, 10 mM in DMSO Leelamine, Pyruvate dehydrogenase kinase (PDK) inhibitor D(+)-DEHYDROABIETYLAMINE Dehydroabietylamine EINECS 215-899-7 1 4A-DIMETHYL-7-ISOPROPYL-1 2 3,4A 9 10 10A-OCTAHYDRO-1-PHENANTHRENE METHYLAMINE DEHYDROABIETHYLAMINE (1R,4aS,10-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl-1-phenanthrenemethanamine) (+)-Dehydroabietylamine ade DehydroabietylamineTech (d)-dehyroabiethylamine ((1R,4aS,10-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine (+)-Dehydroabietylamine (1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)phenanthrene-1α-methanamine ((1S,4aS,10-7-isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine 1-Phenanthrenemethanamine, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10) (1R,4aS,10-1,2,3,4,4a,9,10,10a-Octahydro-1,4adimethyl- 7-(1-methylethyl)-1-phenanthrenemethanamine,d.e (+)-Dehydroabietylamine[OpticaesolvingAgent]> Leelamine Water galbanum 13-trien-15-amine,13-isopropyl-podocpa-11 [Optical Resolving Agent] Dehydroabietylamine > 1-3 C20H31N DEHYDROABIETYLAMINE 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-,[1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine Leelamine free base Leelamine hydrochloride,(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanaminehydrochloride

Description	Leelamine is a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine also inhibits pyruvate dehydrogenase kinases (PDKs). Leelamine exhibits anti-tumor activity[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> PDHK Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	CB1 CB2
References	[1]. Merarchi M, et, al. A Brief Overview of the Antitumoral Actions of Leelamine. Biomedicines. 2019 Jul 19;7(3):53.

Density	1.0±0.1 g/cm3
Boiling Point	382.9±11.0 °C at 760 mmHg
Melting Point	44.50℃
Molecular Formula	C₂₀H₃₁N
Molecular Weight	285.467
Flash Point	156.7±9.1 °C
Exact Mass	285.245636
PSA	26.02000
LogP	6.40
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.528
Storage condition	Desiccate at +4°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP8701000

CHEMICAL NAME :: Podocarpa-8,11,13-trien-15-amine, 13-isopropyl-

CAS REGISTRY NUMBER :: 1446-61-3

BEILSTEIN REFERENCE NO. :: 3084620

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H31-N

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C: Corrosive;Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TP8701000
HS Code	3806900090

31148-95-5

1446-61-3

Literature: Svensk Kemisk Tidskrift, , vol. 66, p. 316,321

1740-19-8

1446-61-3

Literature: Zhurnal Organicheskoi Khimii, , vol. 9, p. 756 - 758,778 - 780

141666-88-8

1446-61-3

Literature: Tetrahedron, , vol. 53, # 42 p. 14355 - 14368

Precursor 2
31148-95-5 1740-19-8
DownStream 1
115269-93-7

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

1231251-18-5	1231251-17-4
1112408-73-7	1156891-31-4
1231251-27-6	1231251-93-6
1231251-94-7	1231251-20-9
1262041-53-1	1231251-73-2