78860-34-1

78860-34-1 structure

Name: Demethylasterriquinone B1
Chemical Name: 5-(7-but-2-enyl-1H-indol-3-yl)-3-hydroxy-2-(2-propan-2-yl-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dione
CAS Number: 78860-34-1
Molecular Formula: C₃₂H₃₀N₂O₄
Molecular Weight: 506.59200
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2016-09-14 23:28:59
Modify Date: 2025-08-27 19:21:13
Demethylasterriquinone B1 is a selective insulin receptor activator. Demethylasterriquinone B1 stimulates tyrosine phosphorylation of the IR β subunit, and the activation of PIK3 and AKT[1].

Name	5-(7-but-2-enyl-1H-indol-3-yl)-3-hydroxy-2-(2-propan-2-yl-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dione
Synonyms	Demethylasterriquinone B1

Description	Demethylasterriquinone B1 is a selective insulin receptor activator. Demethylasterriquinone B1 stimulates tyrosine phosphorylation of the IR β subunit, and the activation of PIK3 and AKT[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> PI3K/Akt/mTOR >> Akt Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor
References	[1]. Li M, et al. Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells. Diabetes. 2001;50(10):2323-2328.