522-51-0
522-51-0 structure
- Name: Dequalinium Chloride
- Chemical Name: dequalinium chloride
- CAS Number: 522-51-0
- Molecular Formula: C30H40Cl2N4
- Molecular Weight: 527.571
- Catalog: API Synthetic anti-infective drugs Disinfectant antiseptic
- Create Date: 2018-05-22 08:00:00
- Modify Date: 2026-06-30 20:41:54
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Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels.Target: Potassium ChannelDequalinium Chloride is a selective blocker of apamin-sensitive K+ channels. Treatment with Dequalinium chloride did not influence conditions caused by haemolytic streptococci -- verified by bacteriological examinations of pharyngeal smears -- inspite of its efficiency in vitro [1]. Dequalinium chloride (DECA), a cationic, lipophilic mitochondrial poison, selectively targets the mitochondrial membrane of certain epithelial carcinoma cells, in which it inhibits cellular energy production. Higher DECA doses under either regimen induced severe toxic effects and mortality [2].
| Name | dequalinium chloride |
|---|---|
| Synonyms |
Quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride
DECA efisol dekamin evazol 1,1'-DECAMETHYLENEBIS(4-AMINOQUINALDINIUM CHLORIDE) DEQUALINIUM CHLORIDE HYDRATE 1,1'-[1,10-Decanediyl] bis[4-amino-2-methylquinolinium chloride] Dequalinium chloride for performance test CRS dequavagyn MFCD00063502 le chlorure de dequalinium DEQUALINIUM DICHLORIDE MitoBloCK-12 Dequalinum decamethylenebis(4-aminoquinaldiniumchloride) 1,1'-Decamethylenebis(2-methyl-4-aminoquinolinium)·dichloride 1,1'-(Decane-1,10-diyl)bis(4-amino-2-methylquinoline-1-ium)·2chloride BADQ-10 polycidine 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride 1,10-decamethylene-bis(4-aminoquinaldiniumchloride) eriosept labost 1,1'-Decane-1,10-diylbis(4-amino-2-methylquinolinium) dichloride dequadinchloride dequavet Dequalinum Chloride QuinoliniuM,1,1'-(1,10-decanediyl)bis[4-amino-2-Methyl-, chloride (1:2) DequaliniuM aMs of bacteria May be) QUINALDINIUM,1,1'-DECAMETHYLENEBIS(4-AMINO-,DICHLORIDE Dequalinium chloride //BP dekadin 1,1'-Decan-1,10-diylbis(4-amino-2-methylchinolinium)dichlorid 1,1'-(1,10-DECANEDIYL)BIS(4-AMINO-2-METHYLQUINOLINIUM) DICHLORIDE dequafungan Decabis ocreme 1,1'-DECAMETHYLENEBIS(4-AMINOQUINALDINIUM) DICHLORIDE Dequalinium chloride CRS Dequalinium for system suitability dequadin Quinolinium, 1,1-(1,10-decanediyl)bis4-amino-2-methyl-, dichloride 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium)·2chloride 1-[10-(4-amino-2-methyl-1-quinolin-1-iumyl)decyl]-2-methyl-4-quinolin-1-iumamine dichloride hydrate Danical Dequadin chloride equaliniumchloride DEQUALINIUM CHLORIDE phylletten 1,1'-(decane-1,10-diyl)bis(4-amino-2-Methylquinolin-1-iuM) chloride eriost Dequalinium chloride for ID EINECS 208-330-9 decamine(phmaceutical) Diquinone chloride 1,1μ-Decamethylenebis(4-aminoquinaldinium) dichloride hydrate optipect baqd10 1,1’-decamethylenebis(4-amino-quinaldiniudichloride Quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, chloride (1:2) Dequalinium (Chloride) |
| Description | Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels.Target: Potassium ChannelDequalinium Chloride is a selective blocker of apamin-sensitive K+ channels. Treatment with Dequalinium chloride did not influence conditions caused by haemolytic streptococci -- verified by bacteriological examinations of pharyngeal smears -- inspite of its efficiency in vitro [1]. Dequalinium chloride (DECA), a cationic, lipophilic mitochondrial poison, selectively targets the mitochondrial membrane of certain epithelial carcinoma cells, in which it inhibits cellular energy production. Higher DECA doses under either regimen induced severe toxic effects and mortality [2]. |
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| Related Catalog | |
| References |
| Melting Point | ≥300 °C(lit.) |
|---|---|
| Molecular Formula | C30H40Cl2N4 |
| Molecular Weight | 527.571 |
| Exact Mass | 526.263000 |
| PSA | 59.80000 |
| LogP | 1.34060 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Hazard Codes | Xi:Irritant; |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | VA0700000 |
| HS Code | 2933499090 |
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |