3886-08-6
3886-08-6 structure
- Name: N-Cbz-L-Glutamic acid 5-tert-butyl ester
- Chemical Name: Z-Glu(OtBu)-OH
- CAS Number: 3886-08-6
- Molecular Formula: C17H23NO6
- Molecular Weight: 337.368
- Catalog: Biochemical Amino acids and their derivatives Glutamic acid derivative
- Create Date: 2018-12-15 14:14:05
- Modify Date: 2026-07-06 17:53:28
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Z-Glu(OtBu)-OH is a derivative of glutamate, can be used for molecule, drug, compounds synthesis[1].
| Name | Z-Glu(OtBu)-OH |
|---|---|
| Synonyms |
(2S)-2-{[(Benzyloxy)carbonyl]amino}-5-tert-butoxy-5-oxopentanoic acid (non-preferred name)
5-tert-butyl ester N-BENZYLOXYCBONYL-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER MFCD00038274 N-cbobenzyloxy-L-glutamic acid gamma-tert-benzyl ester Z-GLU(OTBU)-OH N-ALPHA-BENZYLOXYCBONYL-L-GLUTAMIC-ACID-GAMMA-T-BUTYL ESTER Z-Glu (But) OH N-BENZYLOXYCBONYL-L-GLUTAMIC ACID 5-TERT-BUTYL ESTER N-[(Benzyloxy)carbonyl]-L-glutamic acid hydrogen 5-tert-butyl ester Z-L-GLUTAMIC ACID 5-TERT-BUTYL ESTER Z-GLU(OBUT)-OH Z-L-GLUTAMIC ACID Y-T-BUTYLESTER Cbz-l-glutamate γ- tert-butyl N-CBOBENZOXY-L-GLUTAMIC ACID 5-TERT-BUTYL ESTER Z-L-GLU(TBU)-OH N-ALPHA-BENZYLOXYCBONYL-L-GLUTAMIC-ACID-GAMMA-TERT-BUTYL ESTER L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester, ion(1-) BENZYLOXYCBONYL-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER (2S)-2-{[(Benzyloxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester N-BENZYLOXYCBONYL-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTHER Cbz-L-Glu (γ-But) OH Z-L-GLU(OTBU)-OH N-Benzyloxycbonyl-L-glutamic acid ^y-tert-butyl ester EINECS 223-421-3 5-tert-Butyl N-(Benzyloxycbonyl)-L-glutamate 2-BENZYLOXYCBONYLAMINO-4-TERT-BUTYLPENTANEDIOIC ACID 5-TERT-BUTYL N-CBOBENZOXY-L-GLUTAMATE Z-Glu(OtBu)-OH,N-Cbz-L-glutamic acid γ-t-butyl ester, Z-L-glutamic acid 5-tert-butyl ester N-Benzyloxycarbonyl-L-glutamic acid gamma-tert-butyl ester n-benzyloxycbonyl-l-glutamic acid γ-tert-butyl ester Cbz-L-glutamic acid 5-tert-butyl ester N-Cbz-L-glutamic acid γ-t-butyl ester, Z-L-glutamic acid 5-tert-butyl ester (2S)-2-{[(Benzyloxy)carbonyl]amino}-5-tert-butoxy-5-oxopentanoate Cbz-L-Glu(OtBu)-OH Z-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER (2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-(phenylmethoxycbonylamino)pentanoate (S)-2-(((Benzyloxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid BENZYLOXYCBONYL-L-GLUTAMIC ACID-T-BUTYL ESTER N-Carbobenzoxy-L-glutamic Acid 5-tert-Butyl Ester 5-tert-butyl N-[(phenylmethoxy)carbonyl]-L-glutamate N-[(Phenylmethoxy)carbonyl]-L-glutamic acid 5-(1,1-dimethylethyl) ester Z-L-glutaMic acid-gaMMa-tert-butyl ester N-Benzyloxycbonyl-L-glutamic acid g-tert-butyl ester N-CBZ-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER (2S)-2-{[(Benzyloxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoate N-CBZ-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER N-ALPHA-CBZ-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER CBZ-GLU(OTBU)-OH N-ALPHA-CBOBENZOXY-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER Z-GLUTAMIC ACID(OTBU)-OH N-Cbz-L-glutamic acid γ-t-butyl ester CBZ-L-GLUTAMIC ACID .GAMMA.-TERT.BUTYL ESTER (2S)-2-{[(benzyloxy)carbonyl]amino}-5-(tert-butoxy)-5-oxopentanoic acid N-Cbobenzyloxy-L-glutamic acid γ-t.-butyl ester monohydrate CBZ-GLU(OBUT)-OH N-Cbobenzoxy-L-glutamic Acid 5-tert-Butyl Ester 5-tert-Butyl N-Cbz-L-glutamate N-Cbz-L-glutamic Acid 5-tert-Butyl Ester Z-Glu(OtBu)-OH 5-tert-Butyl N-Cbz-L-glutamate Z-L-glutamic acid γ-tert-butyl ester (HPLC) (2S)-2-{[(benzyloxy)carbonyl]amino}-5-(tert-butoxy)-5-oxopentanoate 5-tert-Butyl N-Carbobenzoxy-L-glutamate (2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-(phenylmethoxycbonylamino)pentanoic acid 5-TERT-BUTYL N-CBZ-L-GLUTAMATE 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate N-CBOBENZOXY-L-GLUTAMIC-GAMMA-TERT-BUTYL ESTER N-Benzyloxycbonyl-L-glutamic acidγ-tert-butyl ester N-Cbz-L-Glutamic acid 5-tert-butyl ester //BP N-CBZ-L-GLUTAMIC ACID 5-TERT-BUTYL ESTER |
| Description | Z-Glu(OtBu)-OH is a derivative of glutamate, can be used for molecule, drug, compounds synthesis[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Shaomeng Wang, et al. Small molecule stat protein degraders. WO2021195481A1 (compound A) |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 522.6±50.0 °C at 760 mmHg |
| Melting Point | 83-87ºC |
| Molecular Formula | C17H23NO6 |
| Molecular Weight | 337.368 |
| Flash Point | 269.9±30.1 °C |
| Exact Mass | 337.152527 |
| PSA | 101.93000 |
| LogP | 3.43 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.524 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H317-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38-43 |
| Safety Phrases | 26-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924299090 |
|
~61%
3886-08-6 |
| Literature: Barbayianni, Efrosini; Fotakopoulou, Irene; Schmidt, Marlen; Constantinou-Kokotou, Violetta; Bornscheuer, Uwe T.; Kokotos, George Journal of Organic Chemistry, 2005 , vol. 70, # 22 p. 8730 - 8733 |
|
~83%
3886-08-6 |
| Literature: Chevallet, Pierre; Garrouste, Patrick; Malawska, Barbara; Martinez, Jean Tetrahedron Letters, 1993 , vol. 34, # 46 p. 7409 - 7412 |
|
~88%
3886-08-6 |
| Literature: Fotakopoulou, Irene; Barbayianni, Efrosini; Constantinou-Kokotou, Violetta; Bornscheuer, Uwe T.; Kokotos, George Journal of Organic Chemistry, 2007 , vol. 72, # 3 p. 782 - 786 |
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~%
3886-08-6 |
| Literature: Tetrahedron Letters, , vol. 34, # 46 p. 7409 - 7412 |
|
~%
3886-08-6 |
| Literature: Tetrahedron Letters, , vol. 30, # 49 p. 6859 - 6860 |
|
~%
3886-08-6 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 673, p. 196 - 207 |
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~%
3886-08-6 |
| Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 82, p. 941 - 953 |
| Precursor 6 | |
|---|---|
| DownStream 6 | |
![L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-,5-(1,1-dimethylethyl) ester structure](https://image.chemsrc.com/caspic/104/79640-76-9.png)
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |