2140-29-6

2140-29-6 structure

Name: Kojibiose
Chemical Name: kojibiose
CAS Number: 2140-29-6
Molecular Formula: C₁₂H₂₂O₁₁
Molecular Weight: 342.29600
Catalog: Research Areas Infection
Create Date: 2018-12-02 06:13:06
Modify Date: 2026-07-09 20:19:02
Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2].

Name	kojibiose
Synonyms	D-Glucose, 2-O-a-D-glucopyranosyl Kojibiose, 10 mM in DMSO α-d-glc-(1→2)-d-glc 2-O-A-D-GLUCOPYRANOSYL-A-D-GLUCOPYRANOSE KOJIBIOSE(RG) 2-O-α-D-Glucopyranosyl-D-glucose Kojibiose >= (HPLC) ALPHA-D-KOJIBIOSE (2R,3S,4R,5R)-3,4,5,6-tetrahydroxy-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-hexanal ALPHA-D-GLC-[1-]-D-GLC (2R,3S,4R,5R)-3,4,5,6-Tetrahydroxy-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal α-D-Glc-D-Glc, 2-O-α-D-Glucopyranosyl-D-glucose Glc1-\|A-2Gal 2-O-ALPHA-D-GLUCOPYRANOSYL-D-GLUCOSE Kojibiose extrapure KOJIBIOSE (2R,3S,4R,5R)-3,4,5,6-tetrahydroxy-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanal (2R,3S,4R,5R)-3,4,5,6-tetrahydroxy-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-hexanal D-Glucose, 2-O-α-D-glucopyranosyl

Description	Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
In Vivo	曲二糖 (0.5 %; w/w 每日摄入饮食; 持续 20 天) 显着改善花生酸 (ARa; 饮食每天 0.3 mg; 持续 20 天) 诱导的肝脏改变的严重程度[1]。 Animal Model: Female Wistar albino rats, aged 3 weeks with Streptozotocin (STZ; HY-13753) two doses of 25 mg/kg per d with a time lapse of 24 h[1] Dosage: 0.5%, w/w Administration: Diet; daily for 20 d Result: Significantly improved the severity of arachidic acid (ARa; 0.3 mg daily for 20 d)-induced hepatic alterations. Significantly increased expression values of PPAR α in comparison with those fed only ARa, suggesting an increased fatty acid metabolism. Showed reduced LPC and PS values than did animals fed only ARa.
References	[1]. José Moisés Laparra, et al. Kojibiose ameliorates arachidic acid-induced metabolic alterations in hyperglycaemic rats. Br J Nutr. 2015 Nov 14;114(9):1395-402. [2]. Miaomiao Wang, et al. Cloning and expression of the sucrose phosphorylase gene in Bacillus subtilis and synthesis of kojibiose using the recombinant enzyme. Microb Cell Fact. 2018 Feb 15;17(1):23.

Density	1.68g/cm3
Boiling Point	783.7ºC at 760mmHg
Molecular Formula	C₁₂H₂₂O₁₁
Molecular Weight	342.29600
Flash Point	292.1ºC
Exact Mass	342.11600
PSA	189.53000
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.652
Storage condition	-20°C

Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3

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