36763-53-8

36763-53-8 structure

Name: Tempone-d16
Chemical Name: 3,3,5,5-tetradeuterio-1-λ1-oxidanyl-2,2,6,6-tetrakis(trideuteriomethyl)piperidin-4-one
CAS Number: 36763-53-8
Molecular Formula: C₉D₁₆NO₂
Molecular Weight: 186.32700
Catalog: Research Areas Others
Create Date: 2019-01-10 12:50:02
Modify Date: 2024-01-05 10:34:59
Tempone-d16 is the deuterium labeled Tempone[1].

Name	3,3,5,5-tetradeuterio-1-λ1-oxidanyl-2,2,6,6-tetrakis(trideuteriomethyl)piperidin-4-one
Synonyms	4-Oxo-2,2,6,6-tetramethylpiperidine-d16,1-15N-1-oxyl 2,2,6,6-tetramethyl-4-piperidone-N-oxyl-d16 Perdeutero-2,2,6,6-tetramethyl-4-piperidon-N-oxid 4-Oxo-TEMPO-d16,1-15N,free radical 4-Oxo-TEMPO-d16,free radical Perdeutero-1-oxyl-2,2,6,6-tetramethyl-4-piperidone TEMPONE-d16,1-15N 4-oxo-2,2,6,6-tetramethylpiperidine-d16-1-oxyl TEMPONE-d16 4-Oxo-,2,2,6,6-tetramethylpiperidine-d16-1-oxyl,TEMPONE-d16 MFCD01075420

Description	Tempone-d16 is the deuterium labeled Tempone[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Melting Point	35ºC(lit.)
Molecular Formula	C₉D₁₆NO₂
Molecular Weight	186.32700
Exact Mass	186.21900
PSA	20.31000
LogP	1.49190

Symbol	GHS09
Signal Word	Warning
Hazard Statements	H400
Precautionary Statements	P273
RIDADR	UN 3077 9 / PGIII
WGK Germany	3

73322-03-9

~84%

36763-53-8

Literature: Yamada, Ken-Ichi; Kinoshita, Yuichi; Yamasaki, Toshihide; Sadasue, Hiromi; Mito, Fumiya; Nagai, Mika; Matsumoto, Shingo; Aso, Mariko; Suemune, Hiroshi; Sakai, Kiyoshi; Utsumi, Hideo Archiv der Pharmazie, 2008 , vol. 341, # 9 p. 548 - 553

666-52-4

36763-53-8

Literature: Drift, E. van der; Rousseeuw, B. A. C.; Smidt, J. Journal of Physical Chemistry, 1984 , vol. 88, # 11 p. 2275 - 2284

Precursor 2
73322-03-9 666-52-4
DownStream 0

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