202197-26-0
202197-26-0 structure
- Name: 3-Chloro-4-[(3-fluorobenzyl)oxy]aniline
- Chemical Name: 3-chloro-4-[(3-fluorophenyl)methoxy]aniline
- CAS Number: 202197-26-0
- Molecular Formula: C13H11ClFNO
- Molecular Weight: 251.684
- Catalog: Pharmaceutical intermediate API intermediate
- Create Date: 2018-12-24 19:51:37
- Modify Date: 2026-07-22 18:52:43
| Name | 3-chloro-4-[(3-fluorophenyl)methoxy]aniline |
|---|---|
| Synonyms |
4-(3-Fluorobenzyloxy)-3-chlorobenzenamine
3-Chloro-4-(3-fluorobenzyloxy)-anilin 3-Chloro-4-(3-fluorobenzyloxy)aniline BenzenaMine, 3-chloro-4-[(3-fluorophenyl)Methoxy] 4-(3-fluorobenzyloxy)-3-chlorobenzenamine 3-Chloro-4-(3-fluorobenzyloxy)-aniline 3-chloro-4-(3-fluoro-benzyloxy)-phenylamine oxy)aniL 4-(3-Fluorobenzyloxy)-3-chlorobenzenamine hydrochloride Lapatinib Impurity 18-d4 3-Chloro-4-((3-fluorobenzyl)oxy)aniline (Lapatinib Impurity) oro-4-(3-fL ZR CG DO1R CF Lapatinib impurity 4 3-Chloro-4-(3-fluorobenzyloxy)aniline 3-Chloro-4-(3-Flurobenzyloxy) PhenylaMine (LTB-A) 3-Chloro-4-[(3-fluorophenyl)methoxy]benzenamine Compound PDK0113 3-Chloro-4-((3-fluorobenzyl) 3-Chloro-4-(3-fluorobenzyloxy)aniline ISO 9001：2015 REACH 3-chloro-4-((3-fluorobenzyl)oxy)aniline Lapatinib genotoxic impurity 1 3-Chloro-4-(3-fluorobenzyloxy)aniline 3-Chloro-4-(3-fluorobenzyloxy)phenylamine 4 - (- chloro - fluorobenzene Methoxy) aniline 3-Chloro-4-(3-fluorobenzyloxy)aniline> LAPATINIB IMP A 3-chloro-4-{[(3-fluorophenyl)methyl]oxy}aniline 3-Chloro-4-[(3-fluorophenyl)Methoxy]benzenaMine 4-(3-Fluorobenzyloxy)- 3-chloroaniline Lapatinib impurity A 3-chloro-4-[(3-fluorophenyl)Methoxy]aniline 3-Chloro-4-(3-fluorobenzyloxy)phenylamine |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 387.9±32.0 °C at 760 mmHg |
| Melting Point | 78.0 to 82.0 °C |
| Molecular Formula | C13H11ClFNO |
| Molecular Weight | 251.684 |
| Flash Point | 188.4±25.1 °C |
| Exact Mass | 251.051315 |
| PSA | 35.25000 |
| LogP | 3.28 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.607 |
| Hazard Codes | Xi |
|---|---|
| RIDADR | 3077 |
| Packaging Group | III |
| HS Code | 2922299090 |
|
~99%
202197-26-0 |
| Literature: Lackey, Karen Elizabeth; Spector, Neil; Wood lll, Edgar Raymond; Xia, Wenle Patent: US2004/53946 A1, 2004 ; |
|
~92%
202197-26-0 |
| Literature: BAYER HEALTHCARE AG Patent: US2010/298297 A1, 2010 ; Location in patent: Page/Page column 14 ; |
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~%
202197-26-0 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 17 p. 4686 - 4691 |
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~%
202197-26-0 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 17 p. 4686 - 4691 |
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~%
202197-26-0 |
| Literature: WO2011/2523 A1, ; WO 2011/002523 A1 |
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202197-26-0 |
| Literature: WO2011/2523 A1, ; WO 2011/002523 A1 |
| Precursor 6 | |
|---|---|
| DownStream 8 | |
![5-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-carbaldehyde structure](https://image.chemsrc.com/caspic/482/231278-84-5.png)
| HS Code | 2922299090 |
|---|---|
| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |