m-PEG3-OMs

Modify Date: 2025-09-01 16:33:17

m-PEG3-OMs Structure
m-PEG3-OMs structure
Common Name m-PEG3-OMs
CAS Number 74654-05-0 Molecular Weight 260.30500
Density N/A Boiling Point N/A
Molecular Formula C8H18O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG3-OMs


m-PEG3-OMs is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name methanesulfonic acid,2-[2-(2-methoxyethoxy)ethoxy]ethanol
Synonym More Synonyms

 m-PEG3-OMs Biological Activity

Description m-PEG3-OMs is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H18O6S
Molecular Weight 260.30500
Exact Mass 260.09300
PSA 110.67000
LogP 0.24310
Storage condition -20°C

 Synthetic Route

~97%

m-PEG3-OMs Structure

m-PEG3-OMs

CAS#:74654-05-0

Literature: Fukase, Koichi; Takashina, Mamoru; Hori, Yumiko; Tanaka, Daizo; Tanaka, Katsunori; Kusumoto, Shoichi Synlett, 2005 , # 15 art. no. U21305ST, p. 2342 - 2346

 Synonyms

triethyleneglycol monomethyl ether methanesulfonate
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