Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: 3,6,9-Trioxaundecanedioic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

13887-98-4

13887-98-4 structure

13887-98-4 structure

Name: 3,6,9-Trioxaundecanedioic acid
Chemical Name: 3,6,9-Trioxaundecanedioic acid
CAS Number: 13887-98-4
Molecular Formula: C₈H₁₄O₇
Molecular Weight: 222.193
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-08 23:03:52
Modify Date: 2026-07-02 06:43:32
369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	3,6,9-Trioxaundecanedioic acid
Synonyms	2,2′-(Oxybis(2,1-ethandiyloxy))bisessigsure Acetic acid, (oxybis(2,1-ethanediyloxy))bis CAS_13-4 2-(2-(Cboxymethoxy)ethoxy)ethoxyacetic acid 2-[2-[2-(Cboxymethoxy)ethoxy]ethoxy]acetic acid 3,6,9-TRIOXAUNDECANEDIOIC ACID 3,6,9 trioxundecanedioic acid Diethylenetrioxydiacetic acid 2,2'-[Oxybis(2,1-ethanediyloxy)]diacetic acid Diethylene glycol bis(cboxymethyl ether) [Oxybis(ethyleneoxy)]bis(acetic acid) SKL081 2,2'-[Oxybis(2,1-ethanediyloxy)] bisacetic acid 3,6,9-Trioxa-1,11-undecanedioic acid Tetraglycolic acid 3,6,9-Trioxaundecadioic acid Acetic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis 3,6,9-Trioxaundecanedioic acid , >= (T) 2,2'-[oxybis(2,1-ethanediyloxy)]bisacetic acid HOOCCH2O-PEG2-CH2COOH/3,6,9-Trioxa-undecanedioic acid trioxaundecanedoicacid 2,2'-[Oxybis(ethane-2,1-diyloxy)]diacetic acid 3,6,9-Trioxaundecanedioic Acid(containing Salt) COOH-CH2-PEG2-CH2-COOH HOOCCH2O-PEG2-CH2COOH 3,6,9-Trioxaundecanedioic acid (TUDS) [Oxybis(ethyleneoxy)]diacetic acid [2-{2-(Cboxymethoxy)ethoxy}ethoxy]acetic acid tetraglycolic acid, 3,6,9-Trioxaundecanedioic acid 2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetic acid Bis-PEG3-acetic acid 3,6,9-Trioxaundecandioic acid CH2COOH-PEG2-CH2COOH 2,2'-((oxybis(ethane-2,1-diyl))bis(oxy))diacetic acid O,O'-OXYDIETHYLENE-DIGLYCOLIC ACID CH2COOH-PEG3-CH2COOH TRIOXAUNDECANEDIOIC ACID Acetic acid, 2,2-oxybis(2,1-ethanediyloxy)bis Einecs -9

Description	369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.3±0.1 g/cm3
Boiling Point	443.7±30.0 °C at 760 mmHg
Molecular Formula	C₈H₁₄O₇
Molecular Weight	222.193
Flash Point	178.3±18.1 °C
Exact Mass	222.073959
PSA	102.29000
LogP	-1.96
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.474

Hazard Codes	Xi: Irritant;
Risk Phrases	41
Safety Phrases	26-39
RIDADR	UN 1760
Packaging Group	III
HS Code	2918990090

211746-77-9 structure

211746-77-9

~98%

13887-98-4 structure

13887-98-4

Literature: Bright, Sandra A.; Brinko, Anne; Larsen, Maja Thim; Sinning, Steffen; Williams, D. Clive; Jensen, Henrik H. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1220 - 1224

112-60-7 structure

112-60-7

~51%

110-99-6 structure

110-99-6

23243-68-7 structure

23243-68-7

13887-98-4 structure

13887-98-4

Literature: Tetrahedron, , vol. 38, # 22 p. 3299 - 3308

112-60-7 structure

112-60-7

~%

13887-98-4 structure

13887-98-4

Literature: Tetrahedron, , vol. 38, # 14 p. 2055 - 2060

Precursor 1
112-60-7
DownStream 4
31255-25-1 93274-34-1 60350-17-6 41775-36-4

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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