868405-37-2

868405-37-2 structure

Name: Protosappanin A dimethyl acetal
Chemical Name: Protosappanin A dimethyl acetal
CAS Number: 868405-37-2
Molecular Formula: C₁₇H₁₈O₆
Molecular Weight: 318.32
Catalog: Natural product Phenols
Create Date: 2017-08-06 12:11:14
Modify Date: 2024-01-13 12:03:30
Protosappanin A dimethyl acetal is a homoisoflavonoid. Protosappanin A dimethyl acetal can be isolated from Caesalpinia sappan. Protosappanin A dimethyl acetal is also a competive inhibitor with significant xanthine oxidase inhibitory activity (IC50=50.7 μM)[1].

Name	Protosappanin A dimethyl acetal
Synonyms	7,7-Dimethoxy-7,8-dihydro-6H-dibenzo[b,d]oxocine-3,10,11-triol 6H-Dibenz[b,d]oxocin-3,10,11-triol, 7,8-dihydro-7,7-dimethoxy-

Description	Protosappanin A dimethyl acetal is a homoisoflavonoid. Protosappanin A dimethyl acetal can be isolated from Caesalpinia sappan. Protosappanin A dimethyl acetal is also a competive inhibitor with significant xanthine oxidase inhibitory activity (IC50=50.7 μM)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase
In Vitro	Protosappanin A dimethyl acetal (0.2-100 μM) dose-dependently inhibits the activity of xanthine oxidase, with a Ki value of 26.9 μM[1].
References	[1]. Nguyen MT, Awale S, Tezuka Y, Tran QL, Kadota S. Xanthine oxidase inhibitors from the heartwood of Vietnamese Caesalpinia sappan. Chem Pharm Bull (Tokyo). 2005 Aug;53(8):984-8.