133410-84-1

133410-84-1 structure

Name: Z-LLY-FMK
Chemical Name: benzyl N-[1-[[1-[[4-fluoro-1-(4-hydroxyphenyl)-3-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
CAS Number: 133410-84-1
Molecular Formula: C₃₀H₄₀FN₃O₆
Molecular Weight: 557.65
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2017-04-27 19:16:08
Modify Date: 2026-07-02 01:23:35
Z-LLY-FMK (Calpain Inhibitor IV) is a calpain inhibitor, involved in apoptosis of many cell systems. Z-LLY-FMK inhibits the intestine apoptosis after common bile duct ligation[1].

Name	benzyl N-[1-[[1-[[4-fluoro-1-(4-hydroxyphenyl)-3-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
Synonyms	Z-LEU-LEU-TYR-FLUOROMETHYLKETONE Z-LLY-FMK/Calpain Inhibitor IV IN1508 L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-[(4-hydroxyphenyl)methyl]-2-oxopropyl] CALPAIN INHIBITOR1 Z-Leu-Leu-Tyr-FMK benzyl N-[(2S)-1-[[(2S)-1-[[(2S)-4-fluoro-1-(4-hydroxyphenyl)-3-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate Z-LEU-LEU-TYR-FMK Z-Leu-Leu-Tyr-Fluoromethylketone FK017 Calpain Inhibitor IV

Description	Z-LLY-FMK (Calpain Inhibitor IV) is a calpain inhibitor, involved in apoptosis of many cell systems. Z-LLY-FMK inhibits the intestine apoptosis after common bile duct ligation[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
Target	Calpain[1]
References	[1]. Sheen-Chen SM, et al. Z-LLY-FMK attenuates intestinal apoptosis after bile duct ligation in rats. Dig Dis Sci. 2009 Nov;54(11):2357-61.