Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ethyl 2-Chloroacetoacetate
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Ethyl 2-Chloroacetoacetate
Price: ￥998.0/500g ￥88.0/25g ￥258.0/100g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ethyl 4-chloroacetoacetate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Ethyl 4-Chloroacetoacetate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Ethyl 2-Chloroacetoacetate
Price: ￥Inquiry/25kg
Purity: 99.0%
Stocking Period: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

638-07-3

638-07-3 structure

Name: Ethyl 2-Chloroacetoacetate
Chemical Name: Ethyl 4-chloroacetoacetate
CAS Number: 638-07-3
Molecular Formula: C₆H₉ClO₃
Molecular Weight: 164.587
Catalog: Chemical reagent Organic reagent Ester Ethyl ester compound
Create Date: 2018-03-13 08:00:00
Modify Date: 2025-08-21 18:12:10

Name	Ethyl 4-chloroacetoacetate
Synonyms	4-chloro ethyl acetoacetate Ethyl4-chloroacetoacetate Ethyl (chloroacetyl)acetate Butanoic acid, 4-chloro-3-oxo-, ethyl ester Butanoic acid, 4-chloro-3-oxo-ethylester Ethyl g-chloroacetoacetate Ethyl-4-chloracetoacetat Ethyl 4-chloroacetoa Ethyl 4-chloro-3-oxobutyrate 4-Chloro-acetoacetic ethyl 2-chloro-acetoacetate Ethyl 4-chloro-3-oxobutanoate MFCD00000939 Ethyl-4chloroacetaacetate Ethyl 2-Chloroacetoacetate Ethyl α-chloroacetoacetate 2-Chloroacetoacetic acid ethyl ester Ethyl 4-chloroacetoacetate EINECS 211-317-0

Density	1.2±0.1 g/cm3
Boiling Point	235.5±0.0 °C at 760 mmHg
Melting Point	-8 °C
Molecular Formula	C₆H₉ClO₃
Molecular Weight	164.587
Flash Point	96.7±0.0 °C
Exact Mass	164.024017
PSA	43.37000
LogP	1.54
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.436
Storage condition	2-8°C
Water Solubility	47.5 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AK5110000

CHEMICAL NAME :: Acetoacetic acid, 4-chloro-, ethyl ester

CAS REGISTRY NUMBER :: 638-07-3

BEILSTEIN REFERENCE NO. :: 1761275

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H9-Cl-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555360

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 108 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,695,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555360

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 88 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,695,1987 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 750 mg/kg/15D-I

TOXIC EFFECTS :: Gastrointestinal - gastritis Gastrointestinal - ulceration or bleeding from stomach Liver - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555360

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H301-H314
Precautionary Statements	P280-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases	R24/25;R34;R51/53
Safety Phrases	S26-S36-S45-S61-S36/37/39
RIDADR	UN 2922 8/PG 2
WGK Germany	3
RTECS	AK5110000
Packaging Group	II
Hazard Class	8
HS Code	2918990090

6082-74-2

~66%

638-07-3

Literature: Terent'ev; Vasil'eva; Mysova; Chakhovskaya Russian Journal of Organic Chemistry, 2004 , vol. 40, # 7 p. 924 - 927

41295-64-1

64-17-5

638-07-3

Literature: EP2518043 A1, ; Page/Page column 10; 11 ;

591-78-6

6082-74-2

~40%

638-07-3

141-97-9

Literature: Russian Journal of Organic Chemistry, , vol. 40, # 7 p. 924 - 927

6082-74-2

100-52-7

~71%

638-07-3

1503-99-7

Literature: Terent'ev; Vasil'eva; Mysova; Chakhovskaya Russian Journal of Organic Chemistry, 2004 , vol. 40, # 7 p. 924 - 927

Precursor 5
6082-74-2 41295-64-1 64-17-5 591-78-6
100-52-7
DownStream 9
106302-03-8 105435-14-1 34265-58-2 40207-03-2
787-07-5 38220-75-6 41051-21-2 59128-02-8
43071-52-9

HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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