2199-87-3
2199-87-3 structure
- Name: 6-bromocoumarin-3-carboxylic acid
- Chemical Name: 6-bromo-2-oxochromene-3-carboxylic acid
- CAS Number: 2199-87-3
- Molecular Formula: C10H5BrO4
- Molecular Weight: 269.04800
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
- Create Date: 2018-09-06 23:05:33
- Modify Date: 2024-01-02 20:22:26
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UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders[1].
| Name | 6-bromo-2-oxochromene-3-carboxylic acid |
|---|---|
| Synonyms |
6-bromo-2-oxo-2H-1-benzopyran-3-carboxylic acid
6-Bromochromon-3-carboxylic acid 6-Bromo-2-oxo-2H-chromene-3-carboxylic acid 6-Bromo-3-carboxycoumarin 6-bromo-2-oxo-2Hchromene-3-carboxylic acid MFCD00047640 6-Bromocoumarin-3-carboxylic acid 6-Bromocoumarin-3-carboxylicAcid |
| Description | UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders[1]. |
|---|---|
| Related Catalog | |
| Target |
NMDA Receptor |
| In Vitro | UBP608 (100 µM) 显示出抑制活性，对 GluN1/GluN2A、GluN1/GluN2B、GluN1/GluN2C、GluN1/GluN2D 的抑制率分别为 89.3%、63.5%、56.1%、23.6%[1]。 |
| References |
| Density | 1.874g/cm3 |
|---|---|
| Boiling Point | 439ºC at 760mmHg |
| Melting Point | 195-198 °C(lit.) |
| Molecular Formula | C10H5BrO4 |
| Molecular Weight | 269.04800 |
| Flash Point | 219.3ºC |
| Exact Mass | 267.93700 |
| PSA | 67.51000 |
| LogP | 2.25370 |
| Vapour Pressure | 1.76E-08mmHg at 25°C |
| Storage condition | room temp |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932209090 |
| Precursor 9 | |
|---|---|
| DownStream 1 | |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |