6-bromocoumarin-3-carboxylic acid

Modify Date: 2024-01-02 20:22:26

6-bromocoumarin-3-carboxylic acid structure	Common Name	6-bromocoumarin-3-carboxylic acid
	CAS Number	2199-87-3	Molecular Weight	269.04800
	Density	1.874g/cm3	Boiling Point	439ºC at 760mmHg
	Molecular Formula	C₁₀H₅BrO₄	Melting Point	195-198 °C(lit.)
	MSDS	Chinese USA	Flash Point	219.3ºC

Use of 6-bromocoumarin-3-carboxylic acid

UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders[1].

Name	6-bromo-2-oxochromene-3-carboxylic acid
Synonym	More Synonyms

Description	UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	NMDA Receptor
In Vitro	UBP608 (100 µM) 显示出抑制活性，对 GluN1/GluN2A、GluN1/GluN2B、GluN1/GluN2C、GluN1/GluN2D 的抑制率分别为 89.3%、63.5%、56.1%、23.6%[1]。
References	[1]. Irvine MW, et al. Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors. Neurochem Int. 2012 Sep;61(4):593-600.

Density	1.874g/cm3
Boiling Point	439ºC at 760mmHg
Melting Point	195-198 °C(lit.)
Molecular Formula	C₁₀H₅BrO₄
Molecular Weight	269.04800
Flash Point	219.3ºC
Exact Mass	267.93700
PSA	67.51000
LogP	2.25370
Vapour Pressure	1.76E-08mmHg at 25°C
Storage condition	room temp

6-bromocoumarin-3-carboxylic acid MSDS(Chinese)

Hazard Codes	Xi: Irritant;
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2932209090

Precursor 9
CAS#:2199-90-8 Ethyl 6-bromo-2... CAS#:2033-24-1 Meldrumic acid CAS#:1761-61-1 5-Bromosalicyla... CAS#:90-02-8 Salicylaldehyde
CAS#:25016-01-7 5-Bromo-2-anisa... CAS#:89228-64-8 6-bromo-N-hydro... CAS#:82486-43-9 Benzaldehyde,5-... CAS#:76693-35-1 6-bromo-3-cyano...
CAS#:141-82-2 Malonic acid
DownStream 1
CAS#:2199-94-2 6-bromo-2-oxo-2...

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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6-Bromocoumarin-3-carboxylic acid

6-Bromocoumarin-3-carboxylicAcid

DC Chemicals Limited
China
Product Name: UBP608
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6-bromocoumarin-3-carboxylic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: ￥210/100 mg

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